NCT03160716

Brief Summary

This is a multi-center, open-label, single-arm study to evaluate an injection tool with Restylane Lyft with Lidocaine for cheek augmentation and correction of age related midface contour deficiencies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 14, 2017

Completed
2 days until next milestone

Study Start

First participant enrolled

May 16, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 19, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2017

Completed
1.5 years until next milestone

Results Posted

Study results publicly available

May 15, 2019

Completed
Last Updated

August 26, 2022

Status Verified

May 1, 2019

Enrollment Period

6 months

First QC Date

May 14, 2017

Results QC Date

April 25, 2019

Last Update Submit

August 24, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Treatment-Emergent Adverse Events [Safety]

    To assess the adverse events (incidence, intensity, and duration) of Restylane® Lyft with Lidocaine in conjunction with the use of a cannula.

    16 weeks

Secondary Outcomes (3)

  • Number of Participants With Aesthetic Improvement

    16 weeks

  • Number of Participants That Responded to Treatment

    16 weeks

  • Subject Satisfaction

    8 weeks

Study Arms (1)

Treatment

OTHER
Device: Restylane Lyft with Lidocaine

Interventions

a sterile gel of hyaluronic acid (HA)

Treatment

Eligibility Criteria

Age22 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects willing to comply with the requirements of the study and providing a signed written informed consent.
  • Males or non-pregnant, non-breastfeeding females, 22 years of age or older.
  • Mild to Substantial Midface Volume Loss

You may not qualify if:

  • Allergy or hypersensitivity to any injectable hyaluronic acid gel or to gram positive bacterial proteins
  • Allergy or hypersensitivity to lidocaine or other amide-type anaesthetics, or topical anaesthetics or nerve blocking agents
  • Undergone prior surgery to midface

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Facial Plastic and Cosmetic Surgery

Beverly Hills, California, 90210, United States

Location

Skin Care and Laser Physicians of Beverly Hills

Los Angeles, California, 90069, United States

Location

Hessler Plastic Surgery

Palo Alto, California, 94306, United States

Location

Union Square Laser Dermatology

New York, New York, 10003, United States

Location

Related Publications (1)

  • Jones DH, Hessler J, Chapas A, Jonas B, Crider J, Chopra R. Microcannula Injection of Large Gel Particle Hyaluronic Acid for Cheek Augmentation and the Correction of Age-Related Midface Contour Deficiencies. Dermatol Surg. 2020 Apr;46(4):465-472. doi: 10.1097/DSS.0000000000002105.

Results Point of Contact

Title
Reception
Organization
Q-Med AB

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 14, 2017

First Posted

May 19, 2017

Study Start

May 16, 2017

Primary Completion

October 31, 2017

Study Completion

October 31, 2017

Last Updated

August 26, 2022

Results First Posted

May 15, 2019

Record last verified: 2019-05

Data Sharing

IPD Sharing
Will not share

Locations