Sedentary Behaviour, Physical Activity and Cardiometabolic Risk in Chronic Obstructive Pulmonary Disease

NCT03157817 | Completed

• 1 other identifier: SPAaRCLUprotocol1.2
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 2

Brief Summary

Investigation into the associations between sedentary behaviour, physical activity, body composition and cardiometabolic risk in COPD. A single assessment visit with fasting blood tests, body composition and strength measures followed by a week of activity monitor wear to record sitting time and physical activity. Cardiometabolic risk markers include fasting glucose, HBA1c, HOMA and lipids and blood pressure.

Conditions

COPD

Outcome Measures

Primary Outcomes (1)

• cardiometabolic risk

  aggregated measure based on lipid levels, fasting glucose, glycated haemoglobin (A1c) (HbA1c), homeostatic model assessment (HOMA) and blood pressure

  baseline

Study Arms (2)

Chronic Obstructive Pulmonary Disease

Patients with a diagnosis of Chronic Obstructive Pulmonary Disease

Healthy Volunteers

Volunteers without any respiratory condition or symptoms

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Those with COPD recruited from both secondary care and an existing primary care database. Healthy volunteers recruited from an existing database recruited through community advertisement.

You may qualify if:

• People with COPD or healthy volunteers without any respiratory conditions
• Over age of 40
• Body Mass Index below 35

You may not qualify if:

• Age below 40
• BMI above 35
• Unable to complete assessment visit

Sponsors & Collaborators

• Loughborough University: lead

Study Sites (2)

Respiratory Biomedical Research Centre

Leicester, Leicestershire, LE3 9QP, United Kingdom

Location

Loughborough Universtiy

Loughborough, Leicestershire, LE11 3TU, United Kingdom

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Week
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 15, 2017
• First Posted: May 17, 2017
• Study Start: October 18, 2016
• Primary Completion: August 15, 2017
• Study Completion: August 15, 2017
• Last Updated: September 1, 2017

Record last verified: 2017-08

Data Sharing

• IPD Sharing: Will not share

Locations

GB (2)