NCT03157011

Brief Summary

the investigators propose to carry out a prospective study consisting of a systematic research of digestive symptoms in patients with SGSp with the validated Global symptom score (GSS) questionnaire, which allowed to grades severity of 10 digestive symptoms (absent, mild, moderate, or severe), asthenia and fever.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
151

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 2, 2017

Completed
15 days until next milestone

First Posted

Study publicly available on registry

May 17, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

July 17, 2017

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 28, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 28, 2018

Completed
Last Updated

April 2, 2026

Status Verified

July 1, 2018

Enrollment Period

12 months

First QC Date

May 2, 2017

Last Update Submit

March 27, 2026

Conditions

Keywords

Primary Sjögren syndrome - Digestive symptoms

Outcome Measures

Primary Outcomes (1)

  • Prevalence of functional digestive symptoms during SGSp

    Measure the prevalence of functional digestive symptoms during SGSp globally and as a function of the duration of the disease

    19 months (End of study)

Secondary Outcomes (5)

  • Prevalence of each GSS symptom

    19 months (End of study)

  • Prevalence of stomach digestive symptoms

    19 months (End of study)

  • Association between the presence of digestive disorders and SGSp activity

    19 months (End of study)

  • Association between the presence of digestive symptoms, the existence of a sicca syndrome at the time of screening

    19 months (End of study)

  • Digestive disorders

    19 months (End of study)

Study Arms (1)

Global symptom score (GSS) questionary

EXPERIMENTAL

systematic research of digestive symptoms in patients with SGSp with Global symptom score (GSS) questionary.

Other: Global symptom score (GSS) questionary

Interventions

systematic research of digestive symptoms in patients with SGSp with Global symptom score (GSS) questionary, which allowed to grades severity of 10 digestive symptoms (absent, mild, moderate, or severe), asthenia and fever.

Global symptom score (GSS) questionary

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with SGSp according to revised American-European criteria
  • Patients 18 years of age or older
  • Patients affiliated to the French social security care system.

You may not qualify if:

  • Patients under measure of maintenance of justice.
  • Patients unable to understand or to participate to the study.
  • Child and major patients making the object of a measure of lawful protection.
  • Patients deprived of freedom.
  • Concomitant interventional clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital, Limoges

Limoges, 87042, France

Location

Related Publications (1)

  • Parreau S, Jacques J, Dumonteil S, Palat S, Geyl S, Gondran G, Bezanahary H, Liozon E, Azais J, Colombie S, Jauberteau MO, Loustaud-Ratti V, Ly KH, Fauchais AL. Abdominal symptoms during Sjogren's syndrome: a pilot study. Adv Rheumatol. 2021 Jan 19;61(1):5. doi: 10.1186/s42358-021-00164-w.

MeSH Terms

Conditions

Sjogren's SyndromeDigestive System Abnormalities

Condition Hierarchy (Ancestors)

Arthritis, RheumatoidArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesXerostomiaSalivary Gland DiseasesMouth DiseasesStomatognathic DiseasesDry Eye SyndromesLacrimal Apparatus DiseasesEye DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System DiseasesDigestive System DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • ANNE-LAURE FAUCHAIS, PH

    University Hospital, Limoges

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: Global symptom score (GSS) questionary . This questionnaire has the advantage of grading the severity of These digestive symptoms.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 2, 2017

First Posted

May 17, 2017

Study Start

July 17, 2017

Primary Completion

June 28, 2018

Study Completion

June 28, 2018

Last Updated

April 2, 2026

Record last verified: 2018-07

Data Sharing

IPD Sharing
Will not share

Locations