NCT03152851

Brief Summary

Aim: to shorten the time of urination by bladder pressure stimulation in children less than 36 months of age who need urinalysis to exclude or diagnose urinary tract infections and to speed up the start time of antibiotics treatment or to eliminate the overcrowding of emergency room(ER) by shortening the time of ER stay.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2016

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2016

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

May 10, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 15, 2017

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2019

Completed
Last Updated

April 18, 2018

Status Verified

April 1, 2018

Enrollment Period

2.2 years

First QC Date

May 10, 2017

Last Update Submit

April 16, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • The urine collection time

    The urine collection time

    up to 2 hours

Secondary Outcomes (4)

  • The antibiotic administration time

    up to 1 day

  • Emergency department(ED) length of stay time

    up to 1 day

  • Comparison between the patients who were diagnosed as actual urinary tract infections and those who were not.

    up to 1 day

  • Complications

    up to 1 month

Study Arms (2)

Pressure stimulus group by ultrasound probe

EXPERIMENTAL

A pressure stimulus would be applied once using a device (ultrasound probe) to the anteroposterior wall of the bladder until the anterior \& posterior wall meet if the measured diameters (AP x T) is 2 X 2 or more by ultrasound

Procedure: Pressure stimulus group

Non-pressure stimulus group

NO INTERVENTION

No pressure stimulus would be given

Interventions

Pressure stimulus group by ultrasound probe

Eligibility Criteria

Age3 Months - 35 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Body temperature of patients ≥ 38℃ reported by guardians
  • No definite focus of fever detected by physical examination
  • Guardian agrees to use urine bag(kismo) collection technique

You may not qualify if:

  • Previous history of urinary tract infections
  • Underlying urinary tract diseases (eg congenital anomalies, neuroblastomas, already diagnosed bladder ureters)
  • ICU treatment indicated
  • Newly diagnosed hydronephrosis on the day of visit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Seoul National Bundang Hospital

Seongnam-si, Gyeonggi-do, 13620, South Korea

RECRUITING

Seoum national university

Seoul, South Korea

RECRUITING

MeSH Terms

Conditions

Urinary Tract Infections

Condition Hierarchy (Ancestors)

InfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Officials

  • JAEYOON JUNG, MD PhD

    The Seoul National University Bundang Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical assistant Professor

Study Record Dates

First Submitted

May 10, 2017

First Posted

May 15, 2017

Study Start

November 1, 2016

Primary Completion

December 31, 2018

Study Completion

March 31, 2019

Last Updated

April 18, 2018

Record last verified: 2018-04

Locations