NCT03148392

Brief Summary

The primary objective is to assess any differences in patient quality of life between Cryo Balloon ablation and Radiofrequency ablation in the treatment of atrial fibrillation. The study will also assess any differences in the amount and duration of pain medication required after the ablation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 27, 2017

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 11, 2017

Completed
5 days until next milestone

Study Start

First participant enrolled

May 16, 2017

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

August 28, 2019

Status Verified

August 1, 2019

Enrollment Period

2.5 years

First QC Date

April 27, 2017

Last Update Submit

August 22, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain Intensity Measurement

    Self report pain intensity measured at baseline and then once a day beginning at least four hours after the ablation. Three individual pain scales will be used. Universal Pain Assessment Tool is scored 0 to 10 with 0 = no pain and 10 = severe.

    7 Days

Secondary Outcomes (2)

  • Health Status and Activity Measurement

    7 Days

  • Pain Medication Assessment

    30 Days

Study Arms (2)

Cryo Balloon Ablation

Arctic Front Advance Cryo Balloon: Mode of ablation determined based on patient and physician preference

Radiofrequency Ablation

Contact Force Sensing Radiofrequency Catheter Ablation: Mode of ablation determined based on patient and physician preference

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Cardiology

You may qualify if:

  • Paroxysmal atrial fibrillation who are advised either Cryoablation or Radiofrequency ablation for treatment.

You may not qualify if:

  • Persistent atrial fibrillation
  • Pregnant
  • Taking pain medications for acute or chronic conditions at the time of the procedure.
  • Undergo a combination of Cryoablation and Radiofrequency ablation
  • Radiofrequency group who undergo ablation beyond pulmonary vein isolation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cardiology Consultants

Pensacola, Florida, 32501, United States

RECRUITING

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Sumit Verma, MD

    Cardiology Consultants

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 27, 2017

First Posted

May 11, 2017

Study Start

May 16, 2017

Primary Completion

November 1, 2019

Study Completion

December 31, 2019

Last Updated

August 28, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations