NCT03146351

Brief Summary

Infant born preterm have an increased risk of adverse long-term developmental outcomes.The risk associated with preterm birth increase as gestational age decreases, and vulnerability remains in moderate and early preterm (\<34 weeks) and late preterm (\>34 weeks). There are many studies in the literature showed that the prevalence of developmental delay increases with premature birth. However, there is no study in the literature investigates effect of early intervention program motor performance in subgroups of preterm infants. Hence the aim of this study is to evaluate the differences in effects of early intervention program on motor development in early and moderate (\<34 weeks) and late preterm infants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2015

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

April 19, 2017

Completed
20 days until next milestone

First Posted

Study publicly available on registry

May 9, 2017

Completed
Last Updated

May 9, 2017

Status Verified

May 1, 2017

Enrollment Period

8 months

First QC Date

April 19, 2017

Last Update Submit

May 8, 2017

Conditions

Keywords

preterminfantphysiotherapy

Outcome Measures

Primary Outcomes (1)

  • Motor performance using the Alberta Infant Motor Scale

    Alberta Infant Motor Scale is used to examine motor performance.

    This study is planned to be completed within 6 months

Study Arms (2)

Early and moderate preterm group

EXPERIMENTAL

Infants born before 34 weeks included in this group

Other: Family based early intervention program (NDT-Bobath based)

Late preterm group

EXPERIMENTAL

Infants born between 34 and 37 weeks included in this group

Other: Family based early intervention program (NDT-Bobath based)

Interventions

Family based early intervention program is NDT - Bobath based home program. Physiotherapist teaches principles of the treatment to infants' family. Family applies the program at home.

Early and moderate preterm groupLate preterm group

Eligibility Criteria

Age1 Day - 6 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Born before 37 gestational weeks,
  • Accepting to join the study
  • Corrected age 6 months or less

You may not qualify if:

  • Having high risk factors (e.g. grade 3 or more intraventricular hemorrhage, PVL, serious seizure)
  • Born after 37 weeks
  • Corrected age greater than 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi Universitesi, Saglik Bilimleri Fakultesi, Fizyoterapi ve Rehabilitasyon Bolumu

Ankara, Turkey (Türkiye)

Location

Related Publications (1)

  • Kyno NM, Ravn IH, Lindemann R, Fagerland MW, Smeby NA, Torgersen AM. Effect of an early intervention programme on development of moderate and late preterm infants at 36 months: a randomized controlled study. Infant Behav Dev. 2012 Dec;35(4):916-26. doi: 10.1016/j.infbeh.2012.09.004. Epub 2012 Oct 11.

    PMID: 23063851BACKGROUND

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: non-randomised clinical trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

April 19, 2017

First Posted

May 9, 2017

Study Start

September 1, 2015

Primary Completion

May 1, 2016

Study Completion

July 1, 2016

Last Updated

May 9, 2017

Record last verified: 2017-05

Locations