Altered MAstication Contribute to TMJ PAin

NCT03139994 | Completed

• 1 other identifier: 20130123
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors. It has been showed an association: a steeper condylar path, flatter lateral anterior guidance, and habitual chewing on the symptomatic side. This finding argues the possibility of causation of some of these characteristics. This double blind longitudinal study aims to assess if the presence of one habitual chewing side could contribute to temporomandibular joint disorders over time. Method. Young adults with no signs or symptoms of TMD will be assessed. Participants with one chewing side (observed and interview); with steeper condylar path and lower lateral guidance angles will be considered consistent one side chewers, and this side will be considered more susceptible to suffer TMD. Mouth opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD.

Conditions

Temporomandibular Joint Disorders; Mastication Disorder

Keywords

occlusion; pain

Outcome Measures

Primary Outcomes (2)

• Presence or not of symptoms of temporomandibular joint disorders according to DC/TMD

  Pain-intensity (0-10 VAS scale, Von Korf)

  At 3 years follow-up

• Change of maximal unassited jaw opening

  Maximum unassisted jaw opening or interincisal distance (from edge to edge) measured by a Boley gauge. Up 38 in females and up 40 mm in males are considered limited.

  Baseline and 3 years follow-up

Secondary Outcomes (5)

• Change of condylar paths angles inclination

  Baseline and 3-4-years follow-up (end of the study)

• Alteration of lateral dental guidance angles

  Baseline and 4-years follow-up (end of the study)

• Change of maximal comfortable jaw opening

  Baseline and 4-years follow-up (end of the study)

• Change of the habitual chewing side

  Baseline and 3-4-years follow-up (end of the study)

• Change of lateral deviation during maximal unassisted jaw opening

  Baseline, 3 years follow-up

Other Outcomes (3)

• Hemimandibular retrognathia

  Baseline

• Hemispheric dominance, asuming oposite side to handedness preference

  Baseline

• Change of Life quality

  Baseline, 3 years follow-up

Interventions

Diagnostic OTHER

OBSERVATIONAL, DIAGNOSTIC PROCEDURES. Young adults with no signs or symptoms of TMD will be assessed. The chewing function, condylar path angles and lateral guidance angles will be recorded. Maximum comfortable and unassisted jaw opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Three-Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD. Same recordings as baseline will be carried out.

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Medical or Dental School students. Healthy young adults with fully dentate normal occlusion

You may qualify if:

• healthies
• full dentates
• normal occlusion
• One habitual chewing side

You may not qualify if:

• Severe malocclusion, dental decay, severe periodontal disease.

Sponsors & Collaborators

• University of Santiago de Compostela: lead

Study Sites (1)

University of Santiago de Compostela

Santiago de Compostela, A Coruña, 15702, Spain

Location

Related Publications (1)

• Santana-Mora U, Lopez-Cedrun J, Mora MJ, Otero XL, Santana-Penin U. Temporomandibular disorders: the habitual chewing side syndrome. PLoS One. 2013 Apr 8;8(4):e59980. doi: 10.1371/journal.pone.0059980. Print 2013.

  PMID: 23593156 RESULT

MeSH Terms

Conditions

Temporomandibular Joint Disorders; Bites and Stings; Pain

Condition Hierarchy (Ancestors)

Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Stomatognathic Diseases; Poisoning; Chemically-Induced Disorders; Wounds and Injuries; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Urbano Santana-Mora, PhD

  University of Santiago de Compostela. Spain

  PRINCIPAL INVESTIGATOR

• Urbano Santana, Prof.

  University of Santiago de Compostela. Spain

  STUDY CHAIR

• Mª Jesús Mora

  University of Santiago de Compostela. Spain

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PROFESSOR

Study Record Dates

• First Submitted: May 10, 2016
• First Posted: May 4, 2017
• Study Start: May 2, 2017
• Primary Completion: October 15, 2018
• Study Completion: October 30, 2018
• Last Updated: October 1, 2021

Record last verified: 2021-09

Data Sharing

• IPD Sharing: Will share

Locations

ES (1)