NCT03137901

Brief Summary

This study test the agreement and precision of Pulse Pressure Variation (PPV) and Cardiac Output (CO) obtained by the Android application Capstesia™ against another pulse contour CO monitoring ( EV-1000, Edwards Lefesciences, USA)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 19, 2017

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 3, 2017

Completed
7 days until next milestone

Study Start

First participant enrolled

May 10, 2017

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2017

Completed
Last Updated

November 26, 2019

Status Verified

November 1, 2019

Enrollment Period

2 months

First QC Date

April 19, 2017

Last Update Submit

November 23, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Agreement and precision of PPV and CO during 5 surgical phases (postinduction, pre incision, postincision, end of surgery and at least one episode of hypotension)

    We will compare PPV and CO given with the EV-1000 and the capstesia app at different phases of the surgery

    during surgery

Interventions

CapstesiaDEVICE

Picture of the arterial waveform taken with a smartphone

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients scheduled for major surgery

You may qualify if:

  • patients scheduled for major surgery which requires a CO and PPV monitoring as standard of care

You may not qualify if:

  • patients with arrhythmias like atrial fibrillation
  • patients with valvular insufficiency

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Erasme

Brussels, 1070, Belgium

Location

Related Publications (1)

  • Joosten A, Jacobs A, Desebbe O, Vincent JL, Sarah S, Rinehart J, Van Obbergh L, Hapfelmeier A, Saugel B. Monitoring of pulse pressure variation using a new smartphone application (Capstesia) versus stroke volume variation using an uncalibrated pulse wave analysis monitor: a clinical decision making study during major abdominal surgery. J Clin Monit Comput. 2019 Oct;33(5):787-793. doi: 10.1007/s10877-018-00241-4. Epub 2019 Jan 3.

Study Officials

  • Alexandre Joosten, M.D

    Erasme

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 19, 2017

First Posted

May 3, 2017

Study Start

May 10, 2017

Primary Completion

June 30, 2017

Study Completion

June 30, 2017

Last Updated

November 26, 2019

Record last verified: 2019-11

Locations