Study of IGRP-specific T Cell in Peripheral Blood of Type 1 Diabetes Mellitus
1 other identifier
observational
30
1 country
1
Brief Summary
10 type 1 diabetes, 10 type 2 diabetes and 10 healthy controls matched with age and sex were enrolled in our study and their periphera blood mononuclear cells (PBMC) were isolated. We implemented ELISPOT(Enzyme-linked Immunospot Assay) to detect the interferon-γ (IFN-γ）which secreted by IGRP-specific T cell. Results were compared between these groups.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jan 2017
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedFirst Submitted
Initial submission to the registry
April 28, 2017
CompletedFirst Posted
Study publicly available on registry
May 2, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2017
CompletedJuly 2, 2017
April 1, 2017
5 months
April 28, 2017
June 28, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
the rate of positive reactivation against the IGRP epitopes
5 months
Study Arms (3)
type 1 diabetes
type 2 diabetes
healthy people
Interventions
Eligibility Criteria
patients of diabetes and healthy controls
You may qualify if:
- the criteria of type 1 and type 2 diabetes
You may not qualify if:
- no diabetes
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Endocrinology, the First Affiliated Hospital to Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 28, 2017
First Posted
May 2, 2017
Study Start
January 1, 2017
Primary Completion
May 30, 2017
Study Completion
May 31, 2017
Last Updated
July 2, 2017
Record last verified: 2017-04
Data Sharing
- IPD Sharing
- Will not share
IPD be shared while request by email