HFHHNOGastric
Does High-Flow Heated and Humidified Nasal Oxygen Therapy (HFHHNO) Result in Gastric Distension? A Two-center Prospective Study
Sponsor study identifier
interventional
60
1 country
1
Study Start
November 6, 2017
Actual (reported)Primary Completion
March 20, 2019
Actual (reported)Study Completion
March 20, 2019
Actual (reported)High Flow Heated and Humidified Nasal Oxygen therapy (HFHHNO) has been increasingly used in emergency medicine to assist patients with short term respiratory failure and to provide adequate oxygen to the body prior to intubation. Gastric distension which is the bloating of the stomach due to air being pumped into it is a concern for anesthesiologists as it increases the risk of nausea and vomiting during surgery (aspiration). The objective of this study is use an ultrasound machine to measure the volume of fluid in the stomach before and after HFNO is used in a standard clinical manner.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 20, 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 16, 2017
Actual (reported)May 1, 2017
Actual (reported)November 6, 2017
Actual (reported)March 20, 2019
Actual (reported)March 20, 2019
Actual (reported)Change in Gastric Volume
Ultrasound scan will be used to determine if there was an increase in gastric fluid volume following session of oxygen therapy.
Prior to, and immediately following session of HFHHNO oxygen therapy.
Gastric Distension
Immediately following session of HFHHNO oxygen therapy.
Participants will undergo one session of high-flow heated and humidified oxygen therapy (HFHHNO) (up to 60-70 litre/min). They will undergo a gastric ultrasound scan after session of HFHHNO therapy.
Participants will undergo one session of high-flow heated and humidified oxygen therapy (HFHHNO) (up to 60-70 litre/min). They will undergo a gastric ultrasound scan after session of HFHHNO therapy.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada
McLellan E, Lam K, Behringer E, Chan V, Bozak D, Mitsakakis N, Perlas A. High-flow nasal oxygen does not increase the volume of gastric secretions during spontaneous ventilation. Br J Anaesth. 2020 Jul;125(1):e75-e80. doi: 10.1016/j.bja.2020.02.023. Epub 2020 Mar 31.
Anahi Perlas, MD
University Health Network, Toronto
60 participants (actual enrollment reported by the registry).
First Submitted
February 16, 2017
First Posted
May 1, 2017
Study Start
November 6, 2017
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
March 20, 2019
Actual (reported)Study Completion
March 20, 2019
Actual (reported)Last Updated
September 10, 2019
Record last verified: 2019-02
No IPD is to be shared with other researchers. All data will be obtained during an gastric ultrasound scan.
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Source: ClinicalTrials.gov.
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