NCT03132688

Brief Summary

This retrospective study the safety and efficacy of intravenous propofol used in children under 2 years of age during general anesthesia for surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

April 20, 2017

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 22, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 22, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 28, 2017

Completed
Last Updated

April 28, 2017

Status Verified

April 1, 2017

Enrollment Period

2 days

First QC Date

February 21, 2017

Last Update Submit

April 26, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • Safety: blood pressure

    blood pressure

    Intraoperative 1 day

  • Safety: blood pressure

    blood pressure

    Intraoperative 7th days

Secondary Outcomes (1)

  • Bispectral index

    Intraoperative

Study Arms (1)

children < 2 years old

Children under 2 years of age who received intravenous propofol during general anesthesia.

Drug: Propofol

Interventions

Intravenous administration with dose of 100-200mcg/kg/min

children < 2 years old

Eligibility Criteria

AgeUp to 2 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children who underwent surgery From September 2013 to December 2016 , and received intravenous propofol for general anesthesia will be enrolled.

You may qualify if:

  • Children under 2 years of age
  • Children who received intravenous propofol for maintenance of anesthesia

You may not qualify if:

  • Children who underwent general anesthesia with inhalational anesthetics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SNUH

Seoul, Jongro Gu, 15710, South Korea

Location

MeSH Terms

Conditions

Bradycardia

Interventions

Propofol

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PhenolsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsOrganic Chemicals

Study Officials

  • Hee-Soo Kim, PhD

    Seoul National University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 21, 2017

First Posted

April 28, 2017

Study Start

April 20, 2017

Primary Completion

April 22, 2017

Study Completion

April 22, 2017

Last Updated

April 28, 2017

Record last verified: 2017-04

Locations