Vitamin D Supplementation and Immunity/Physical Performance
The Effect of Vitamin D Supplementation on Vitamin D Status, Immunity and Physical Performance
1 other identifier
interventional
260
1 country
1
Brief Summary
The purpose of this study is to examine the effect of vitamin D supplementation on vitamin D status, immunity and physical performance.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2016
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 6, 2016
CompletedFirst Submitted
Initial submission to the registry
March 30, 2017
CompletedFirst Posted
Study publicly available on registry
April 27, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 28, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2017
CompletedApril 27, 2017
April 1, 2017
1.3 years
March 30, 2017
April 24, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Vitamin D status
Circulating 25-hydroxy-vitamin D, 1,25-d OH(OH)D
Up to 20 months
Secondary Outcomes (5)
Physical performance 1
Up to 20 months
Physical performance 2
Up to 20 months
Physical performance 3
Up to 20 months
Hepatitis B antibody
Up to 20 months
Mucosal immunity
Up to 20 months
Study Arms (4)
Solar simulated radiation (SSR)
EXPERIMENTALSolar simulated radiation (SSR)
Placebo SSR
PLACEBO COMPARATORPlacebo SSR
Oral Vitamin D3
EXPERIMENTALOral Vitamin D3
Placebo Oral Vitamin D3
PLACEBO COMPARATORPlacebo Oral Vitamin D3
Interventions
Eligibility Criteria
You may qualify if:
- Passed medical assessment by medical doctor
You may not qualify if:
- Medically deferred by medical doctor
- Regular sun bed use
- Holiday in a hot sunny climate in \<3 months
- Regular vitamin D supplementation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Bangor Universitylead
- University of East Angliacollaborator
- University of Manchestercollaborator
Study Sites (1)
Infantry Training Centre
Catterick, North Yorkshire, DL9 3PS, United Kingdom
Related Publications (1)
Kashi DS, Oliver SJ, Wentz LM, Roberts R, Carswell AT, Tang JCY, Jackson S, Izard RM, Allan D, Rhodes LE, Fraser WD, Greeves JP, Walsh NP. Vitamin D and the hepatitis B vaccine response: a prospective cohort study and a randomized, placebo-controlled oral vitamin D3 and simulated sunlight supplementation trial in healthy adults. Eur J Nutr. 2021 Feb;60(1):475-491. doi: 10.1007/s00394-020-02261-w. Epub 2020 May 10.
PMID: 32390123DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 30, 2017
First Posted
April 27, 2017
Study Start
January 6, 2016
Primary Completion
April 28, 2017
Study Completion
August 31, 2017
Last Updated
April 27, 2017
Record last verified: 2017-04
Data Sharing
- IPD Sharing
- Will not share