Sonographic Evaluation of Patients With Carpal Tunnel Syndrome Following Steroid Injection

NCT03132051 | Unknown

• 1 other identifier: 2016-07-006A; 2012-05-021A
• Study Type: interventional
• Target: 54
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study was to assess sonographic changes of the median nerve after steroid injection for carpal tunnel syndrome.

Conditions

Carpal Tunnel Syndrome

Keywords

carpal tunnel syndrome

Outcome Measures

Primary Outcomes (1)

• Cross sectional area

  The CSA of the median nerve was measured at 2 levels: at the carpal tunnel inlet (CSA-I; immediately prior to the proximal margin of the flexor retinaculum) and in the mid-carpal tunnel (CSA-M; at the level of the pisiform bone and scaphoid tubercle)

  12 weeks

Secondary Outcomes (6)

• flattening ratio

  2, 6, 12 weeks

• Boston Carpal Tunnel Questionnaire (BQ)

  2, 6, 12 weeks

• Median nerve distal motor latency

  2, 6, 12 weeks

• sensory nerve conduction velocity

  2, 6, 12 weeks

• compound muscle action potential amplitude (CMAP)

  2, 6, 12 weeks

Study Arms (1)

steroid injection

EXPERIMENTAL

ultrasound-guided steroid injection using 1ml of 10 mg (10mg/ml) triamcinolone acetonide

Drug: steroid injection

Interventions

steroid injection DRUG

ultrasound-guided steroid injection using 1ml of 10 mg (10mg/ml) triamcinolone acetonide

Also known as: triamcinolone acetonide

steroid injection

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• clinical diagnosis of CTS
• The diagnosis of CTS was confirmed by electrophysiological tests.

You may not qualify if:

• neurologic disorders that could mimic CTS such as cervical radiculopathy, polyneuropathy, proximal median nerve entrapment, or thoracic outlet syndrome
• history of distal radius fracture
• pregnancy or lactation
• regular use of systemic NSAIDs or corticosteroids
• known allergy to corticosteroids and local anesthetics.

Sponsors & Collaborators

• Taipei Veterans General Hospital, Taiwan: lead

Study Sites (1)

Teipei Veterans General Hospital

Taipei, Taiwan

RECRUITING

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Steroids; Triamcinolone Acetonide

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Fused-Ring Compounds; Polycyclic Compounds; Triamcinolone; Pregnadienes; Pregnanes; Steroids, Fluorinated

Study Officials

• Jia chi Wang

  Taipei Veteran General hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jia chi Wang, MD

CONTACT

886-2-28757361; jcwang0726@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Model Details: All patients received steroid injection for carpel tunnel syndrome (CTS) and ultrasonographic evaluation before and after steroid injection

Study Record Dates

• First Submitted: February 16, 2017
• First Posted: April 27, 2017
• Study Start: April 1, 2013
• Primary Completion: February 1, 2018
• Study Completion: February 1, 2018
• Last Updated: April 27, 2017

Record last verified: 2017-02

Locations

TW (1)