The Association of Omentin and Ischemic Stroke
1 other identifier
observational
2,000
1 country
1
Brief Summary
This observational study aims to research whether there is a relationship between omentin and ischemic stroke on the aspects of incidence, severity, and recovery etc.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2017
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedFirst Submitted
Initial submission to the registry
April 1, 2017
CompletedFirst Posted
Study publicly available on registry
April 24, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2025
CompletedApril 24, 2017
April 1, 2017
9 years
April 1, 2017
April 21, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
the odds ratio of omentin plasma concentration between cases and controls
The circulation level of omentin will be assessed in cases and controls. Then the odds ratio will be statically analysed to detect whether omentin is asociated with ischemic stroke on protein level.
up to 3 years
the frequency difference of single nucleotide polymorphism(SNP) of omentin in the enrolled subjects
The SNP will be analysed in the recruited subjects. And the the frequency difference will be calculated to explore if any SNP is related to ischemic stroke.
up to 3 years
Secondary Outcomes (5)
the NIHSS assessed for functional outcome of stroke
up to 3 years
the modified Rankin Scale assessed for functional disability
up to 3 years
the Barthel index assessed for functional independence in activities
up to 3 years
the number of all cause death
up to 3 years
the number of re-stroke in case group
up to 3 years
Study Arms (2)
Control
patients without any history of stroke
Ischemic Stroke
patients with an episode of neurological dysfunction caused by focal cerebral, spinal, or retinal infarction within 72 hours.
Eligibility Criteria
the study population is from primary care clinic, physical examination center, and social volunteers.
You may qualify if:
- For ischemic stroke group,acute clinically defined ischemic stroke
- For control group, without any history of stroke
You may not qualify if:
- For ischemic stroke group
- Hemorrhagic Stroke
- Previous Ischemic Stroke For control group
- The expected life expense less than 3 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Xi'an No.3 Hospital
Xi’an, Shanxi, 710018, China
Biospecimen
Whole Blood
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Tian Ye, PhD
Xi'an No.3 Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 1, 2017
First Posted
April 24, 2017
Study Start
January 1, 2017
Primary Completion
December 31, 2025
Study Completion
December 31, 2025
Last Updated
April 24, 2017
Record last verified: 2017-04
Data Sharing
- IPD Sharing
- Will share