Quantitative Renal Uptake Using TC99m DMSA in Hypertensive &/or Diabetic Patients.

NCT03123237 | Unknown Phase 4

• 1 other identifier: DMSA
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

the investigators explore the possible role of DMSA to detect renal affection in diabetic \&/or hypertensive patients by detecting difference in counts using Tc 99m DMSA in control \& diabetic \&/or hypertensive patients.

Conditions

Diabetes Mellitus; Hypertension

Outcome Measures

Primary Outcomes (1)

• Renal Counts

  Quantitative Tc99m DMSA renal scan using SPECT technique will be used to measure renal function.

  2-4 hours

Study Arms (4)

Control

PLACEBO COMPARATOR

control will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Diagnostic Test: DMSA scan

Diabetic

ACTIVE COMPARATOR

diabetic cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Diagnostic Test: DMSA scan

Hypertensive

ACTIVE COMPARATOR

hypertesive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Diagnostic Test: DMSA scan

Diabetic & Hypertensive

ACTIVE COMPARATOR

Diabetic \& Hypertensive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Diagnostic Test: DMSA scan

Interventions

DMSA scan DIAGNOSTIC_TEST

We explore the possible role of DMSA to detect renal affection in diabetic \&/or hypertensive patients by detecting difference in counts using Tc 99m DMSA in control \& diabetic \&/or hypertensive patients.

Control; Diabetic; Diabetic & Hypertensive; Hypertensive

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with diabetes (type2), weather controlled or not.
• Patients with essential hypertension.
• Patients with diabetes \& hypertension.
• Within normal renal function (urea \& creatinine).
• Control cases may be normal individuals (apparently healthy) like donors for renal transplant.

You may not qualify if:

• Patients with abnormal renal function.
• Patients with diseases known to affect kidney function rather diabetes \& hypertension e.g. SLE, heart failure or liver cell failure.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut university

Asyut, Egypt

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus; Hypertension

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Heba Askar, MsC

CONTACT

+201003040898; hebaaskar@aun.edu.eg

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle investigator

Study Record Dates

• First Submitted: April 15, 2017
• First Posted: April 21, 2017
• Study Start: July 1, 2016
• Primary Completion: October 1, 2017
• Study Completion: December 1, 2017
• Last Updated: April 21, 2017

Record last verified: 2017-04

Locations

EG (1)