Trials Sponsors Conditions Drugs Pricing

Conditions

Diurnal Variation of Paracetamol Excretion

Outcome Measures

Primary Outcomes (1)

Changes in the amount of urinary paracetamol in different times
Changes in the amount of urinary paracetamol in different times (morning, midday and night) 4 hours after oral administration of 500 mg of paracetamol
[Morning: 0 hour (baseline), 4 hour (end); Mid-day: 0 hour (baseline), 4 hour (end); Night: 0 hour (baseline), 4 hour (end)] [Safety Issue: No]

Study Arms (3)

Paracetamol 500 mg tablet at Morning

OTHER

Urinary paracetamol of 41 healthy volunteers will be measured after oral administration at morning

Drug: Paracetamol 500 mg tablet at morning

Paracetamol 500 mg tablet at Midday

OTHER

Urinary paracetamol of 41 healthy volunteers will be measured after oral administration at midday

Drug: Paracetamol 500 mg tablet at midday

Paracetamol 500 mg tablet at Night

OTHER

Urinary paracetamol of 41 healthy volunteers will be measured after oral administration at night

Interventions

Paracetamol 500 mg tablet at morningDrug

Single dose oral paracetamol will be administered at 8.00 am

Also known as: Tablet. Ace

Paracetamol 500 mg tablet at Morning

Paracetamol 500 mg tablet at middayDrug

Single dose oral paracetamol will be administered at 2.00 pm

Also known as:

Eligibility Criteria

Age19 Years - 23 Years

Sexmale(Gender-based eligibility)

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

The healthy male student volunteers of Eastern Medical College having age range between 19 and 23 years

You may not qualify if:

Sponsors & Collaborators

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Otherlead

Study Sites (1)

Eastern Medical College

Comilla, 3500, Bangladesh

MeSH Terms

Interventions

Acetaminophen

Intervention Hierarchy (Ancestors)

AcetanilidesAnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Study Officials

Mir Misbahuddin, PhD
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
STUDY DIRECTOR

Enrollment

46 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NON RANDOMIZED
Masking: NONE
Purpose: DIAGNOSTIC
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor

Study Record Dates

First Submitted

April 17, 2017

First Posted

April 21, 2017

Study Start

November 3, 2016

Actual (reported)

Estimation of Paracetamol in Urine to Assess the Diurnal Variation

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (3)

Paracetamol 500 mg tablet at Morning

Paracetamol 500 mg tablet at Midday

Paracetamol 500 mg tablet at Night

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (3)

Paracetamol 500 mg tablet at Morning

Paracetamol 500 mg tablet at Midday

Paracetamol 500 mg tablet at Night

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations