NCT03118934

Brief Summary

The purpose of this study is to compare an alternative fitting guide to a current fitting guide for optimizing contact lens parameters and determining contact lens prescription.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
188

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable

Geographic Reach
3 countries

20 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 11, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 18, 2017

Completed
29 days until next milestone

Study Start

First participant enrolled

May 17, 2017

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 7, 2017

Completed
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 28, 2017

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

September 26, 2018

Completed
Last Updated

September 26, 2018

Status Verified

August 1, 2018

Enrollment Period

2 months

First QC Date

April 11, 2017

Results QC Date

July 3, 2018

Last Update Submit

August 28, 2018

Conditions

Keywords

contact lensespresbyopiamultifocal

Outcome Measures

Primary Outcomes (1)

  • Mean Number of Trial Lenses Needed to Fit Each Eye

    The Investigator used a multi-focal contact lens fitting guide to determine which study lens to fit

    VIsit 1/Day 1

Study Arms (3)

AOA MF

EXPERIMENTAL

Lotrafilcon B multifocal contact lenses worn bilaterally (in both eyes) for 10 ± 3 days

Device: Lotrafilcon B multifocal contact lenses

DACP MF

EXPERIMENTAL

Nelfilcon A multifocal contact lenses worn bilaterally for 10 ± 3 days

Device: Nelfilcon A multifocal contact lenses

DT1 MF

EXPERIMENTAL

Delefilcon A multifocal contact lenses worn bilaterally for 10 ± 3 days

Device: Delefilcon A multifocal contact lenses

Interventions

Contact lenses for near, intermediate, and distance correction worn on a daily wear basis and cared for with participant's habitual lens care solution

Also known as: AIR OPTIX AQUA® Multifocal
AOA MF

Contact lenses for near, intermediate, and distance correction worn on a daily disposable basis (removed every night and discarded) with a new pair of study lenses every morning

Also known as: DAILIES® AquaComfort Plus® Multifocal
DACP MF

Contact lenses for near, intermediate, and distance correction worn on a daily disposable basis (removed every night and discarded) with a new pair of study lenses every morning

Also known as: DAILIES TOTAL1® Multifocal
DT1 MF

Eligibility Criteria

Age40 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Sign informed consent;
  • Normal eyes;
  • Current full-time soft contact lens wearer needing presbyopia correction;
  • Willing to wear lenses for a minimum of five days per week, six hours per day, and attend all study visits;

You may not qualify if:

  • Use of systemic or ocular medications for which contact lens wear could be contraindicated as determined by the Investigator;
  • Eye conditions (past or present) as specified in the protocol;
  • Currently wearing Alcon multifocal (MF) contact lenses;
  • Only one eye with functional vision;
  • Contact lens wear in one eye only;
  • Use of mechanical eyelid therapy or eyelid scrubs within 14 days before Visit 1 and not willing to discontinue during the study;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (20)

Alcon Investigative Site

Phoenix, Arizona, 85032, United States

Location

Alcon Investigative Site

San Diego, California, 92123, United States

Location

Alcon Investigative Site

Pensacola, Florida, 32503, United States

Location

Alcon Investigative Site

Tallahassee, Florida, 32308, United States

Location

Alcon Investigative Site

Pittsburg, Kansas, 66762, United States

Location

Alcon Investigative Site

Shawnee Mission, Kansas, 66204, United States

Location

Alcon Investigative Site

Ann Arbor, Michigan, 48105, United States

Location

Alcon Investigative Site

Eden Prairie, Minnesota, 55344, United States

Location

Alcon Investigative Site

Medina, Minnesota, 55340, United States

Location

Alcon Investigative Site

Raytown, Missouri, 64133, United States

Location

Alcon Investigative Site

Powell, Ohio, 43065, United States

Location

Alcon Investigative Site

Warwick, Rhode Island, 02888, United States

Location

Alcon Investigative Site

Memphis, Tennessee, 38104, United States

Location

Alcon Investigative Site

Memphis, Tennessee, 38119, United States

Location

Alcon Investigative Site

Burnaby, British Columbia, V5E 1G3, Canada

Location

Alcon Investigative Site

Toronto, Ontario, M2N 3A4, Canada

Location

Alcon Investigative Site

Toronto, M2J2Z1, Canada

Location

Alcon Investigative Site

Coventry, CV49PQ, United Kingdom

Location

Alcon Investigative Site

Hereford, HR1 2PR, United Kingdom

Location

Alcon Investigative Site

Monmouth, NP25 3PS, United Kingdom

Location

MeSH Terms

Conditions

PresbyopiaRefractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Results Point of Contact

Title
Head, CDMA Vision Care Franchise
Organization
Alcon, A Novartis Division

Study Officials

  • Clinical Trial Manager, Vision Care

    Alcon Research

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Subjects are unmasked to the study lenses that are dispensed, but will be masked to the fitting guides used to fit each eye.
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2017

First Posted

April 18, 2017

Study Start

May 17, 2017

Primary Completion

July 7, 2017

Study Completion

July 28, 2017

Last Updated

September 26, 2018

Results First Posted

September 26, 2018

Record last verified: 2018-08

Data Sharing

IPD Sharing
Will not share

Locations