NCT03111199

Brief Summary

The purpose of this study is to analyze the effects of TENS Burst combined Cryotherapy on painful sensation, functional capacity and quality of life of patients with non-specific chronic pain. Study hypothesis: The TENS Burst combined with Cryotherapy offers a better response in the pain sensation, functional capacity and quality of life of patients with non-specific chronic low back pain when compared to the application of these resources in isolation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 17, 2017

Completed
26 days until next milestone

First Posted

Study publicly available on registry

April 12, 2017

Completed
5 days until next milestone

Study Start

First participant enrolled

April 17, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2017

Completed
Last Updated

April 12, 2017

Status Verified

April 1, 2017

Enrollment Period

6 months

First QC Date

March 17, 2017

Last Update Submit

April 6, 2017

Conditions

Keywords

Low back painAnalgesiaPhysical therapy

Outcome Measures

Primary Outcomes (4)

  • Change from baseline Pain evaluated by Visual Analog Scale at 1 month

    Evaluated from the participants' response to pain questioning on the visual analog scale.

    1 month

  • Change from baseline Pain evaluated by Visual Analog Scale at 2 months

    Evaluated from the participants' response to pain questioning on the visual analog scale.

    2 months

  • Change from baseline Pain evaluated by algometry at 1 month

    To evaluate the pain by the pain sensation through the pressure algometer.

    1 month

  • Change from baseline Pain evaluated by algometry at 2 months

    To evaluate the pain by the pain sensation through the pressure algometer.study completion

    2 months

Study Arms (4)

Control Placebo Group

PLACEBO COMPARATOR

The subjects of this group will be submitted to TENS bound in placebo mode in the lumbar spine.

Other: TENS Burst PlaceboOther: Education

Cryotherapy Group

EXPERIMENTAL

The subjects of this group will be submitted to Cryotherapy in the lumbar spine.

Other: CryotherpyOther: Education

TENS Burst Group

EXPERIMENTAL

The subjects of this group will be submitted to TENS Burst in the lumbar spine.

Other: TENS Burst PlaceboOther: Education

TENS Burst and Cryotherapy Group

EXPERIMENTAL

The subjects of this group will be submitted to TENS Burst and Cryotherapy in the lumbar spine.

Other: CryotherpyOther: TENS BurstOther: Education

Interventions

Cryotherapy will be used by means of ice packs over a painful region. The ice will be crushed inside a bag so that it is in an ideal size that provides a coupling in a painful column in the lumbar spine; Once it has been inserted in the plastic bag and before closing it all the air must be removed to avoid a faster thawing of the ice and have difficulties of coupling.

Cryotherapy GroupTENS Burst and Cryotherapy Group

The TENS Burst therapy will be performed using the KLD Sonophasys EUS 0503 electrotherapy device connected in the current therapy mode with the following parameters: 4Hz frequency, high pulse duration of 200 μsec and the current intensity will be at the maximum amplitude To generate visible muscle contraction without generating pain / discomfort. A channel will be used using self-adhesive electrodes arranged parallel to the erector muscle of the spine, so that the region to be treated is between the electrodes.

TENS Burst and Cryotherapy Group

The TENS Burst placebo therapy will be performed using the KLD Sonophasys EUS 0503 electrotherapy device connected in the current therapy mode with the following parameters: 4Hz frequency, high pulse duration of 200 μsec and the current intensity will be on but without Produce the effects of visible muscle contractions because the channel will not be properly coupled in the apparatus so that the stimulation does not reach the patient. A channel will be used using self-adhesive electrodes arranged parallel to the erector muscle of the spine, so that the region to be treated is between the electrodes.

Control Placebo GroupTENS Burst Group

After the electrophysical intervention, a moment of education and awareness will be held, in which the participants will receive information about the purpose of the treatment; Anatomy and biomechanics of the lumbar spine; Chronic non-specific back pain; Cognitive, emotional, genetic, social, and lifestyle factors; Intrinsic and extrinsic physical factors, biopsychosocial model: beliefs of pain and hypervigilance; Concepts of joint protection; Energy conservation and general guidelines.

Also known as: Lesson
Control Placebo GroupCryotherapy GroupTENS Burst GroupTENS Burst and Cryotherapy Group

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Women who present a regular menstrual cycle of 21-35 days;
  • Body mass index between 18.5 and 30 kg / m2;
  • Low back pain for at least 12 weeks;
  • Diagnosis for the treatment of chronic lumbar of non-specific origin;
  • Not used electrotherapy before;
  • No presenting skin alteration, vascular sensitivity or that hinder a perception of electrical stimulation and allergy to ice.

You may not qualify if:

  • Those who are not tolerant and respect the evaluation and / or intervention procedures;
  • Absence in less than two protocol treatment sessions;
  • Initiate during the protocol the use of analgesics and anti-inflammatories;
  • The participants to withdraw their consent to participate in the research.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Federal University of Rio Grande do Norte

Natal, Rio Grande do Norte, 59072-970, Brazil

Location

MeSH Terms

Conditions

Low Back PainAgnosia

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPerceptual DisordersNeurobehavioral ManifestationsNervous System Diseases

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Central Study Contacts

Wouber H de Brito Vieira, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 17, 2017

First Posted

April 12, 2017

Study Start

April 17, 2017

Primary Completion

October 1, 2017

Study Completion

November 1, 2017

Last Updated

April 12, 2017

Record last verified: 2017-04

Locations