Phenomenological and Psychopathological Factors Associated to Hallucinations in Parkinson's Disease

NCT03105401 | Terminated

• 1 other identifier: 69HCL17_0137
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to describe hallucinations prevalence in a sample of patients affected by Parkinson's disease and consulting in an outpatient facility. An unique one hour interview will be offered to volunteers patients. Patients participating to the study will be asked to answer a semi-structured questionnaire searching for hallucinations of all modalities, minor psychotic symptoms and delusions. Psychometric scales will be assessed to search for depressive symptoms, cognitive impairment and specific personality characteristics. The study hypothesis is that hallucinations prevalence in Parkinson's disease is underestimated and is higher than usually described in the scientific literature when all hallucinations modalities and minor hallucinatory phenomenons are searched for.

Conditions

Parkinson Disease

Outcome Measures

Primary Outcomes (1)

• Hallucinations Prevalence

  Semi-structured questionnaire precisely describing hallucinations of all modalities and their characteristics, as well as minor hallucinations and delusions. Binary Yes/No possible answers. Unique 1 hour interview to assess semi-structured questionnaire for primary outcome measurement, and psychometric scales.

  1 hour

Study Arms (1)

Patients affected by Parkinson's disease

Outpatients affected by Parkinson's Disease consulting in neurology can be included if volunteer

Other: Assessment of hallucinations in Parkinson's disease

Interventions

Assessment of hallucinations in Parkinson's disease OTHER

Patients participating to the study will be asked to answer a semi-structured questionnaire searching for hallucinations of all modalities, minor psychotic symptoms and delusions. Psychometric scales will be assessed to search for depressive symptoms, cognitive impairment and specific personality characteristics.

Patients affected by Parkinson's disease

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Outpatients affected by Parkinson's Disease consulting in neurology can be included if volunteer

You may qualify if:

• Age ≥ 18 years-old
• Absence of opposition from the patient himself/herself or his/her legal representant for his/her participation to the study
• Patient without superior age limit with a diagnosis of Parkinson's disease made according to the UKPDSBB criteria (UK Parkinson's Disease Society Brain Bank clinical diagnostic criteria)
• Outpatient consulting in neurology at the Charpennes'hospital

You may not qualify if:

• Opposition to the study
• Deafness or blindness which could compromise the interview

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hôpital des Charpennes. Centre de Recherche Clinique - vieillissement, cerveau, fragilité

Villeurbanne, 69100, France

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Jing XIE, MD

  Hôpital des Charpennes. Centre de Recherche Clinique - vieillissement, cerveau, fragilité

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 4, 2017
• First Posted: April 10, 2017
• Study Start: May 15, 2017
• Primary Completion: April 25, 2018
• Study Completion: April 25, 2018
• Last Updated: January 17, 2019

Record last verified: 2019-01

Locations

FR (1)