NCT03103308

Brief Summary

This study will determine if a structured walking intervention will help maintain or improve physical activity levels, physical function and quality of life in hematopoietic stem cell transplant patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable cancer

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 17, 2017

Completed
20 days until next milestone

First Posted

Study publicly available on registry

April 6, 2017

Completed
1 month until next milestone

Study Start

First participant enrolled

May 16, 2017

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 15, 2018

Completed
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2018

Completed
Last Updated

April 6, 2018

Status Verified

April 1, 2018

Enrollment Period

10 months

First QC Date

March 17, 2017

Last Update Submit

April 5, 2018

Conditions

Keywords

CancerExercisePhysical Function

Outcome Measures

Primary Outcomes (1)

  • The Physical Performance Test Battery

    Physical Function

    10 minutes

Secondary Outcomes (2)

  • Functional Assessment of Cancer Therapy: Bone Marrow Transplant Questionaire Related Quality of Life

    20 minutes

  • Patient Reported Outcome Measurement Information System

    20 minutes

Study Arms (2)

Walk training and transplant

EXPERIMENTAL

Multidirectional walk training with activity monitoring after bone marrow transplant

Other: Walk Training and Transplant

Activity Monitoring and transplant

EXPERIMENTAL

Activity monitoring alone after bone marrow transplant.

Other: Activity Monitoring and Transplant

Interventions

Subjects will receive free activity monitors and have three training sessions per week for the duration of their bone marrow transplant treatment

Walk training and transplant

Subjects will receive free activity monitors for the duration of their bone marrow transplant treatment

Activity Monitoring and transplant

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be between 40 and 80 years of age
  • Willing and able to provide written informed consent in English
  • Ability to comprehend the purpose of the study
  • Be scheduled to receive an autologous or allogeneic hematopoietic stem cell transplant at Sylvester Comprehensive Cancer Center
  • Have an expected hospital stay of at least 2 weeks
  • Not currently be participating in an exercise training program

You may not qualify if:

  • Dementia, altered mental status, or psychiatric condition
  • Received erythropoiesis-stimulating proteins within 4 weeks prior to enrollment
  • Comorbid conditions that would contraindicate exercise testing
  • Undergoing concurrent non-transplant-related chemotherapy or radiation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sylvester Comprehensive Cancer Center

Miami, Florida, 33136, United States

Location

MeSH Terms

Conditions

NeoplasmsMotor Activity

Interventions

Transplantation

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Surgical Procedures, Operative

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 17, 2017

First Posted

April 6, 2017

Study Start

May 16, 2017

Primary Completion

March 15, 2018

Study Completion

April 1, 2018

Last Updated

April 6, 2018

Record last verified: 2018-04

Locations