NCT03092973

Brief Summary

Epistaxis is a very frequent emergency among adults and often needs specialised treatment in an ENT-department. Among others, atherosclerosis is often named as a reason for an increased risk for Epistaxis. To evaluate whether or not this is the case, the investigators examined the carotid intima media thickness via ultrasound in patients who were treated in the ENT-department of the University Hospital of Zurich.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2016

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2016

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

March 22, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 28, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2017

Completed
Last Updated

October 30, 2017

Status Verified

October 1, 2017

Enrollment Period

7 months

First QC Date

March 22, 2017

Last Update Submit

October 26, 2017

Conditions

EpistaxisAtherosclerosis

Outcome Measures

Primary Outcomes (1)

  • Carotid Intima Media Thickness in Epistaxis vs. Controls

    June 2017

Study Arms (2)

Epistaxis Group

Diagnostic Test: Ultrasound

Control Group

Diagnostic Test: Ultrasound

Interventions

UltrasoundDIAGNOSTIC_TEST
Control GroupEpistaxis Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

50 patients with epistaxis and 50 healthy controls.

You may qualify if:

  • active or very recently active anterior or posterior epistaxis
  • at least 18 years old

You may not qualify if:

  • posttraumatic or postoperative epistaxis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital of Zurich

Zurich, Canton of Zurich, 8091, Switzerland

Location

Related Publications (1)

  • Kunz SM, Holzmann D, Soyka MB. Association of epistaxis with atherosclerotic cardiovascular disease. Laryngoscope. 2019 Apr;129(4):783-787. doi: 10.1002/lary.27604. Epub 2018 Dec 13.

    PMID: 30549051DERIVED

MeSH Terms

Conditions

EpistaxisAtherosclerosis

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Nose DiseasesRespiratory Tract DiseasesOtorhinolaryngologic DiseasesHemorrhagePathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms, RespiratorySigns and SymptomsArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Diagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Study Officials

  • Michael Soyka, PD Dr. med.

    University of Zurich

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 22, 2017

First Posted

March 28, 2017

Study Start

December 1, 2016

Primary Completion

June 30, 2017

Study Completion

June 30, 2017

Last Updated

October 30, 2017

Record last verified: 2017-10

Data Sharing

IPD Sharing
Will not share

The participant data will no longer be used by us or other researchers after the project is finished.

Locations

CH(1)