NCT03092063

Brief Summary

The overall objective of this study is to construct an adaptive intervention that integrates family members and patients as partners in care while promoting diabetes self-management for Mexican Americans with Type 2 diabetes. The project incorporates four evidence-based, culturally tailored treatments using a Sequential, Multiple Assignment Randomized Trial to help determine what sequence of intervention strategies work most efficiently and for whom.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
330

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2017

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

March 10, 2017

Completed
17 days until next milestone

First Posted

Study publicly available on registry

March 27, 2017

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2021

Completed
Last Updated

September 29, 2021

Status Verified

September 1, 2021

Enrollment Period

3.8 years

First QC Date

March 10, 2017

Last Update Submit

September 28, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Diabetes Self-Management Behaviors (Revised Summary of Diabetes Self-Care Activities)

    This 11-item scale assesses ADA-recommended health activities in diet, exercise, glucose self-monitoring, medication adherence and foot care. The mean number of days in the past week that activities are performed is calculated on a scale of 0-7; a high mean score indicates better diabetes self-management.

    This outcome measure will be assessed at baseline, six weeks, three months, six months and 12 months. The primary outcome is change from baseline as compared to the subsequent assessment points.

Secondary Outcomes (5)

  • Diabetes Self-Efficacy (Stanford Self-Efficacy Scale)

    This outcome measure will be assessed at baseline, three months, six months and 12 months.

  • Diabetes knowledge (Spoken Knowledge in Low Literacy Patients with Diabetes scale)

    This outcome measure will be assessed at baseline, three months, six months and 12 months.

  • Family Support (Diabetes Family Support Behavior Checklist)

    This outcome measure will be assessed at baseline, three months, six months and 12 months.

  • Collaborative goal setting (Patient Assessment of Chronic Illness Care)

    This outcome measure will be assessed at baseline, three months, six months and 12 months.

  • Glycemic control

    This outcome measure will be assessed at baseline, three months, six months and 12 months.

Study Arms (6)

Tomando Control-Nurse

EXPERIMENTAL

Tomando Control de su Diabetes-Nurse is a culturally tailored, community-based, Diabetes Self-Management program delivered in a group format by licensed nurses working with individual patients and families.

Behavioral: Tomando Control-Nurse

Tomando Control-Promotora

EXPERIMENTAL

Tomando Control de su Diabetes-Promotora is a culturally tailored, community-based, Diabetes Self-Management program delivered in a group format by community health workers (promotoras) working with individual patients and families.

Behavioral: Tomando Control-Promotora

Enhanced Engagement-Nurse

EXPERIMENTAL

Tomando Control de su Diabetes-Nurse is a culturally tailored, community-based, Diabetes Self-Management program delivered in a group format by licensed nurses working with individual patients and families. If subjects do not benefit sufficiently, the subject may be randomized to receive three home visits to facilitate engagement with treatment.

Behavioral: Tomando Control-NurseBehavioral: Enhanced engagement

Enhanced Engagement-Promotora

EXPERIMENTAL

Tomando Control de su Diabetes-Promotora is a culturally tailored, community-based, Diabetes Self-Management program delivered in a group format by licensed nurses working with individual patients and families. If subjects do not benefit sufficiently, the subject may be randomized to receive three home visits to facilitate engagement with treatment.

Behavioral: Tomando Control-PromotoraBehavioral: Enhanced engagement

Multifamily Group-Promotora

EXPERIMENTAL

If subjects do not benefit sufficiently from the initial Tomando Control intervention offered by the promotoras, they may be randomized to receive a multifamily group intervention consisting of three components: three initial "joining" sessions conducted with each of the families separately; a one-day (six hour) educational workshop; and ongoing multifamily group sessions.

Behavioral: Tomando Control-PromotoraBehavioral: Multifamily Group

Multifamily Group-Nurses

EXPERIMENTAL

If subjects do not benefit sufficiently from the initial Tomando Control intervention offered by the nurses, they may be randomized to receive a multifamily group intervention consisting of three components: three initial "joining" sessions conducted with each of the families separately; a one-day (six hour) educational workshop; and ongoing multifamily group sessions.

Behavioral: Tomando Control-NurseBehavioral: Multifamily Group

Interventions

Tomando Control de su Diabetes-Nurse is a community-based intervention given in six 2.5 hour sessions. The Spanish-language sessions are led by two trained Registered Nurses. Subjects covered in these sessions include: 1) techniques to deal with the symptoms of diabetes and associated conditions; 2) appropriate exercise; 3) healthy eating; 4) correct use of diabetes medications; and 5) working more effectively with health care providers in a collaborative partnership. Participants make weekly action plans, share experiences, and help each other solve problems they encounter in creating and carrying out their self-management strategies.

Enhanced Engagement-NurseMultifamily Group-NursesTomando Control-Nurse

Tomando Control de su Diabetes-Promotora is a community-based intervention given in six 2.5 hour sessions. The Spanish-language sessions are led by two trained promotoras. Subjects covered in these sessions include: 1) techniques to deal with the symptoms of diabetes and associated conditions; 2) appropriate exercise; 3) healthy eating; 4) correct use of diabetes medications; and 5) working more effectively with health care providers in a collaborative partnership. Participants make weekly action plans, share experiences, and help each other solve problems they encounter in creating and carrying out their self-management strategies.

Enhanced Engagement-PromotoraMultifamily Group-PromotoraTomando Control-Promotora

The Tomando Control clinician (either a promotora or a Registered Nurse, depending on the original group assignment), will conduct up to three home visits that are designed to explain the purpose of the TC intervention to a key relative so as to re-engage the family member in the group process

Enhanced Engagement-NurseEnhanced Engagement-Promotora

The multifamily group consists of three components: three initial "joining" sessions conducted with each of the families separately; a one-day (six hour) educational workshop; and ongoing multifamily group sessions.

Multifamily Group-NursesMultifamily Group-Promotora

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Mexican origin and speaks Spanish fluently
  • age 18 years or older
  • medical chart diagnosis of Type 2 diabetes
  • living with at least one adult family member who is willing to participate.

You may not qualify if:

  • diagnosis of Type 1 diabetes
  • participation in another Diabetes Self-management education program within the past 12 months
  • pregnancy
  • significant cognitive impairment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Olive View-UCLA Medical Center

Sylmar, California, 91342, United States

Location

Related Publications (2)

  • Kopelowicz A, Wali S, Polzin R, Ruiz ME, Nandy K. Promotore-Led Versus Registered Nurse-Led Diabetes Self-Management Education in Mexican Americans: A Randomized Clinical Trial. Sci Diabetes Self Manag Care. 2023 Oct;49(5):374-383. doi: 10.1177/26350106231192353. Epub 2023 Aug 18.

  • Kopelowicz A, Nandy K, Ruiz ME, Polzin R, Kurator K, Wali S. Improving Self-management of Type 2 Diabetes in Latinx Patients: Protocol for a Sequential Multiple Assignment Randomized Trial Involving Community Health Workers, Registered Nurses, and Family Members. JMIR Res Protoc. 2023 Jan 16;12:e44793. doi: 10.2196/44793.

MeSH Terms

Interventions

Psychotherapy, Group

Intervention Hierarchy (Ancestors)

Socioenvironmental TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • alex kopelowicz, MD

    Olive View-UCLA Education & Research Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Raters are blind to treatment condition.
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Model Details: Diabetes Self-Management Education
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Psychiatry

Study Record Dates

First Submitted

March 10, 2017

First Posted

March 27, 2017

Study Start

March 1, 2017

Primary Completion

December 31, 2020

Study Completion

July 31, 2021

Last Updated

September 29, 2021

Record last verified: 2021-09

Locations