NCT03077984

Brief Summary

This project is one multi-center, a prospective cohort study, based on 1660 cases of ischemic stroke patients with the treatment of 3 months, and 21 months of follow-up observation in order to clarify the advantages and characteristics of integrated treatment of traditional Chinese medicine sequela of apoplexy; With the formation of curative effect, to highlight the advantage of the programme of comprehensive treatment of apoplectic sequela in traditional Chinese medicine and its compound preparation; To form a active medical service mode of stroke chronic disease management processes, as well as modalities and mechanisms for the evaluation of the curative effect.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,660

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started Jan 2017

Longer than P75 for not_applicable stroke

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

January 24, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 13, 2017

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

March 14, 2017

Status Verified

January 1, 2017

Enrollment Period

1.9 years

First QC Date

January 24, 2017

Last Update Submit

March 13, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • recurrence rate of ischemic stroke

    In this paper 1660 cases of ischemic stroke patients with integrated traditional Chinese medicine therapy for 3 months, And 21-month follow-up observation To identify the traditional Chinese medicine comprehensive treatment to reduce mortality in patients with ischemic stroke recurrence rate, to improve the degree of disability of limbs after stroke and the effect of the main symptom of sequelae.

    to observe the recurrence rate of ischemic stroke 1 year later

  • improve the degree of disability of limbs after ischemic stroke

    In this paper 1660 cases of ischemic stroke patients with integrated traditional Chinese medicine therapy for 3 months, And 21-month follow-up observation To identify the traditional Chinese medicine comprehensive treatment to improve the degree of disability of limbs after stroke and the effect of the main symptom of sequelae.

    to observe the degree of disability of limbs after ischemic stroke 2 year later

Study Arms (2)

the cohort of Chinese medicine treatment

EXPERIMENTAL

The cohort of Chinese medicine treatment uses its comprehensive program of TCM on the basis of treatment with western medicine, including Chinese Herbs, acupuncture and acupoint application therapies.

Combination Product: Chinese medicine treatment

the cohort of western medicine treatment

NO INTERVENTION

The cohort of Western medicine treatment refers to the treatment of cerebrovascular disease prevention and cure guideline of China-related programmes, including anti-platelet aggregation, blood pressure,blood glucose,Blood Lipids lowering therapies.

Interventions

Chinese medicine treatmentCOMBINATION_PRODUCT

The cohort of Chinese medicine treatment uses its comprehensive program of TCM on the basis of treatment with western medicine, including Chinese Herbs, acupuncture and acupoint application therapies.

the cohort of Chinese medicine treatment

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients in accordance with the criteria for the diagnosis of cerebral infarction.
  • Functional Defects of Extremities1≤MRS≤5.
  • Age between 18 and 75 years old (including 18 and 75), No gender limitation.
  • Patients who agreed to participate in clinical trials and signed the informed consent form.
  • Patients with stable vital signs after two weeks.

You may not qualify if:

  • Patients with cerebral infarction at acute phase.
  • Patients with cerebral infarction, transient ischemic attack, cerebral hemorrhage and cerebral arteritis.
  • Patients with AF, ain tumor, brain trauma, brain parasite disease and rheumatic heart disease.
  • Patients with bleeding or severe bleeding within 3 months.
  • Patients with severe hepatitis, Kidneys, blood and the metabolic system diseases.
  • Pisabilities and viewers with NIHSS prescribed by law.(Physical disabilities such as blind, deaf, dumb, mental disorder, mental disorder).
  • Patients with history of alcohol and drug abuse, will reduce the possibility or make it hard into the Project Group according to the researchers' judgment.
  • Allergic constitutions and drug sensitivities.
  • Patients in other clinical trials or clinical trials of other drugs for more than 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 24, 2017

First Posted

March 13, 2017

Study Start

January 1, 2017

Primary Completion

December 1, 2018

Study Completion

December 1, 2020

Last Updated

March 14, 2017

Record last verified: 2017-01

Data Sharing

IPD Sharing
Will share