NCT03077035

Brief Summary

The study was to monitor effectiveness of glass ionomer sealant and resin-based sealant in ICDAS, and to evaluat the correlation between ICDAS and DIAGNOdent over 24 months. Over 200 8-year-old children with at least 2 permanent molar with the International Caries Detection and Assessment System (ICDAS) scores 0-4 were placed glass ionomer sealant and resin-based sealant split-mouthed randomly, and examined with ICDAS and DIAGNOdent before sealents placement and 6, 12 and 24 months after.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

February 23, 2017

Completed
15 days until next milestone

First Posted

Study publicly available on registry

March 10, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2017

Completed
Last Updated

March 21, 2017

Status Verified

March 1, 2017

Enrollment Period

2 years

First QC Date

February 23, 2017

Last Update Submit

March 19, 2017

Conditions

Keywords

ICDASDIAGNOdentglass ionomer sealantresin-based sealantpit and fissure sealantseffectiveness of preventing caries

Outcome Measures

Primary Outcomes (3)

  • Change in Decayed Surfaces (DS) of Different Fissure Sealants

    Count of DS in different ICDAS cut-off( including D1-6S, D1-2S, D3-6S, D4-6S and D5-6S) in the baseline and 6-month, 12-month and 24-month follow-up.

    Baseline, 6 months, 12 months and 24 months

  • Change in Repaired Sealants by the baseline ICDAS

    Evaluation the numbers of tooth surface in which the fissure sealants were in the status partially retained or completely lost, and ICDAS score were increasing from the baseline to the 3 follow-ups.

    6 months, 12 months and 24 months

  • Change in DIAGNOdent Score

    The peak value of DIAGNOdent was recorded after repeating it 3 times in the baseline and 3 follow-ups

    Baseline, 6 months, 12 months and 24 months

Study Arms (2)

glass ionomer sealant

EXPERIMENTAL
Other: glass ionomer sealants

resin-based sealant

ACTIVE COMPARATOR
Other: resin-based sealant

Interventions

glass ionomer sealant
resin-based sealant

Eligibility Criteria

Age7 Years - 9 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Subjects provided written informed consent;
  • They were 7 to 9 years old;
  • They have at least 2 permanent molar with the International Caries Detection and Assessment System (ICDAS) scores 0-4;
  • They were generally heallthy

You may not qualify if:

  • They were allergic to the constituents in pit and fissure sealants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Stomatology The Fourth Military Medical University

Xi'an, Shaanxi, 710032, China

RECRUITING

MeSH Terms

Conditions

Van der Woude syndrome

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Director, Preventive Dentistry Department, Clinical Professor

Study Record Dates

First Submitted

February 23, 2017

First Posted

March 10, 2017

Study Start

October 1, 2015

Primary Completion

October 1, 2017

Study Completion

November 1, 2017

Last Updated

March 21, 2017

Record last verified: 2017-03

Locations