Acute Pancreatitis Patient Registry To Examine Novel Therapies In Clinical Experiences 2
APPRENTICE2
1 other identifier
observational
1,183
1 country
1
Brief Summary
This study is an ancillary of APPRENTICE. This will be the international based study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2015
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2015
CompletedFirst Submitted
Initial submission to the registry
February 2, 2017
CompletedFirst Posted
Study publicly available on registry
March 9, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 4, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 4, 2020
CompletedMay 6, 2020
May 1, 2020
4.3 years
February 2, 2017
May 5, 2020
Conditions
Outcome Measures
Primary Outcomes (2)
Number of patients with pancreatic necrosis as assessed by their clinical course.
Evaluation of the existing risks, predictive scores, and markers of severe disease.
12 months
Number of patients with persistent organ failure as assessed by their clinical course.
Evaluation of the current management and outcomes of acute pancreatitis around the world.
12 months
Study Arms (1)
Patients with Acute Pancreatitis
Patients with Acute Pancreatitis
Interventions
Eligibility Criteria
Patients with Acute Pancreatitis
You may qualify if:
- The diagnosis of AP based upon presence of two out of the three following criteria:
- Abdominal pain typical to AP
- Serum amylase or lipase levels more than three times the upper limit of normal
- Imaging findings suggestive of AP
- Willingness to participate in the study and ability to sign informed consent by patient or his/her proxy (if unable to speak).
You may not qualify if:
- Age under 18 years
- Unwilling to provide consent by patient or his/her proxy
- Presence of pancreatic cancer
- Presence of chronic pancreatitis
- Occurrence of AP following a multiple trauma episode
- Having history of organ transplant
- Presence of any cancer which required chemotherapy or radiation therapy in the past year.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
UPMC Presbyterian
Pittsburgh, Pennsylvania, 15213, United States
Biospecimen
Specimens will be collected to look at biological measures.
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Georgios I Papachristou, MD
University of Pittsburgh
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Medicine
Study Record Dates
First Submitted
February 2, 2017
First Posted
March 9, 2017
Study Start
December 1, 2015
Primary Completion
March 4, 2020
Study Completion
March 4, 2020
Last Updated
May 6, 2020
Record last verified: 2020-05