Economic Evaluation Comparing CCT With MMT in Hai Phong City, Vietnam

NCT03071315 | Completed

• 1 other identifier: HC12259
• Study Type: observational
• Target: 522
• Locations: 1 country
• Sites: 1

Brief Summary

The study compared the effectiveness and cost-effectiveness of two dominant heroin dependence treatment approaches: center-based compulsory rehabilitation (CCT) and community-based voluntary methadone treatment (MMT) in Hai Phong City, Vietnam. The design was a combined retrospective and prospective, non-randomized cohort over three years (with data at five time-points). The study was conducted between 2012 and 2015, involving 208 CCT participants and 384 MMT participants with heroin dependence.

Conditions

Heroin Dependence

Keywords

Economic evaluation; Heroin dependence; Compulsory treatment; Methadone treatment; Vietnam; East and Southeast Asia; Cost-effectiveness

Outcome Measures

Primary Outcomes (1)

• Heroin abstinence

  Free from heroin use (self-reported), confirmed by urine drug screening on interview day.

  Preceding 3 months and 30 days

Secondary Outcomes (5)

• Drug-free days

  Preceding 3 months and 30 days

• Drug-use related illegal behaviors

  Preceding 3 months and 30 days

• Drug-use related blood-borne virus (BBV) risk behaviors

  Preceding 3 months and 30 days

• Overdose incidents

  Preceding 3 months and 30 days

• Monthly drug spending

  Preceding 3 months and 30 days

Study Arms (2)

CCT participants

Center-based compulsory treatment (CCT) participants who were placed into compulsory treatment centers for two years for a range of punitive treatment such as education, moral teaching, labor work. Very basic health care is provided in the CCT centers.

Other: CCT

MMT participants

Methadone maintenance treatment (MMT) participants who have been receiving MMT treatment. In Hai Phong City, during the period of this study, voluntary MMT was provided in the community free for people who were assessed as dependent on heroin.

Other: MMT

Interventions

CCT OTHER

CCT focuses on behavioral approach, mainly punitive punishment measures.

CCT participants

MMT OTHER

MMT is a combination of pharmaceutical and behavioral intervention.

MMT participants

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

CCT Participants: Participants who were placed in three CCT centers in Hai Phong City for 2 years (2011-2013) and agreed to voluntarily participate in this study (from July 2013: 12 months community follow-up). MMT Participants: Participants who have participated in a previous cohort study (two-years:2009-2012) and agreed to voluntarily participate in this study (from 2013: an addition of 12 months)

You may qualify if:

• years of age and older
• Heroin dependent
• CCT-released participants who were rehabilitated in the CCT centers under the compulsory track.
• CCT-released participants who received the recruitment letter sent by CCT centers' staff and who could provide either the recruitment letter or a certificate of CCT treatment completion at the time of first contact with a researcher as a proof that they were newly CCT-released participants.
• Consented voluntarily to participate in the study, as assessed and determined by the researcher providing the informed consent documentation.

You may not qualify if:

• Younger than 18 years old
• Severe cognitive or mental impairment
• Unable to grant consent for this research study
• Non-dependent use of heroin.
• years of age and older
• Heroin dependence, measured by self-reported daily use of heroin during 3 months prior to index treatment, a proxy to measure heroin dependence
• Participated in MMT treatment in Hai Phong City from 2008-2009
• Consented voluntarily to participate in this research, as assessed and determined by the researcher providing the informed consent documentation.
• Younger than 18 years old
• Severe cognitive or mental impairment
• Unable to grant consent for this research study
• Non-dependent use of heroin.

Sponsors & Collaborators

• The University of New South Wales: lead
• The Atlantic Philanthropies: collaborator
• FHI 360: collaborator
• Hanoi Medical University: collaborator
• University of Adelaide: collaborator

Study Sites (1)

Study site in Vietnam

Haiphong, Hai Phong, 10000, Vietnam

Location

Related Publications (1)

• Vuong T, Ritter A, Shanahan M, Ali R, Nguyen N, Pham K, Vuong TTA, Le GM. Outcomes of compulsory detention compared to community-based voluntary methadone maintenance treatment in Vietnam. J Subst Abuse Treat. 2018 Apr;87:9-15. doi: 10.1016/j.jsat.2018.01.011. Epub 2018 Jan 16.

  PMID: 29471930 DERIVED

MeSH Terms

Conditions

Heroin Dependence

Interventions

2-methylcyclopentadienyl manganese tricarbonyl

Condition Hierarchy (Ancestors)

Opioid-Related Disorders; Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Officials

• Alison Ritter, PhD

  The University of New South Wales

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 28, 2017
• First Posted: March 6, 2017
• Study Start: January 20, 2013
• Primary Completion: January 30, 2015
• Study Completion: January 30, 2015
• Last Updated: March 13, 2017

Record last verified: 2017-03

Data Sharing

• IPD Sharing: Will not share

Locations

VN (1)