NCT03070626

Brief Summary

Administration of preoperative oral carbohydrates are suggested to reduce insulin resistance due to surgical stress. The aim of this study is to investigate whether preoperative oral carbohydrate loading can contribute to lower incidence of postoperative discomfort and to reduce complications in elective lung cancer patients undergoing video assisted thorascopic surgery (VATS).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
104

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2017

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 3, 2017

Completed
17 days until next milestone

Study Start

First participant enrolled

March 20, 2017

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2020

Completed
Last Updated

March 27, 2017

Status Verified

March 1, 2017

Enrollment Period

2.8 years

First QC Date

January 20, 2017

Last Update Submit

March 24, 2017

Conditions

Keywords

General SurgeryCarbohydratesPerioperative

Outcome Measures

Primary Outcomes (1)

  • Postoperative discomfort measured by the questionnaire "Quality of recovery 40" (QoR-40) measured on the first postoperative day.

    Postoperative discomfort measured by the questionnaire "Quality of recovery 40" (QoR-40) measured on the first postoperative day.

    First postoperative day

Secondary Outcomes (4)

  • Gastrointestinal discomfort postoperatively.

    First seven postoperative days.

  • Heart rhythm disturbances postoperatively.

    First seven postoperative days.

  • Time to mobilization.

    First seven postoperative days.

  • Length of stay

    First seven postoperative days.

Study Arms (2)

Interventional group

EXPERIMENTAL

Carbohydrate-rich, dietary supplement: PreOp® 800ml day before surgery and PreOp® 400ml 2-4hours preoperative.

Dietary Supplement: PreOp®

Control group

NO INTERVENTION

Standard of care: Fasting from 24hours (midnight), night before surgery.

Interventions

PreOp®DIETARY_SUPPLEMENT

No preoperative drink.

Also known as: NutriciaPreOp®
Interventional group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adult patients undergoing elective video-assisted thoracoscopic surgery due to lung neoplasms.
  • ability to understand and speak Norwegian

You may not qualify if:

  • impaired gastric emptying
  • diabetes
  • ongoing treatment for pain
  • ongoing infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oslo University Hospital

Oslo, Oslo County, 0450, Norway

RECRUITING

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Per Reidar Woldbæk, MD, PhD

CONTACT

Astrid B. Krohn-Hansen, bachelor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

January 20, 2017

First Posted

March 3, 2017

Study Start

March 20, 2017

Primary Completion

January 1, 2020

Study Completion

January 1, 2020

Last Updated

March 27, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

Locations