NCT03069729

Brief Summary

The goal of this research is to develop better tools for diagnosing illness of the feet and legs of people who have diabetes. Investigators will use thermal videos of the foot to aid in the refinement of a system designed to detect signs of diabetic peripheral neuropathy (DPN). The team of investigators will also look at diabetic eye disease and how it might relate to diabetic foot disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
331

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 16, 2017

Completed
15 days until next milestone

First Posted

Study publicly available on registry

March 3, 2017

Completed
5 days until next milestone

Study Start

First participant enrolled

March 8, 2017

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2019

Completed
Last Updated

October 12, 2020

Status Verified

October 1, 2020

Enrollment Period

2.4 years

First QC Date

February 16, 2017

Last Update Submit

October 7, 2020

Conditions

Keywords

screen

Outcome Measures

Primary Outcomes (1)

  • Pattern of thermal recovery

    The thermal recovery pattern after cold provocation will be different for each group studied.

    24 months

Secondary Outcomes (1)

  • Correlation of DPN severity levels and DR severity levels

    18 months

Study Arms (3)

Control group

non-diabetic; no intervention

Other: no intervention

Diabetics without DPN

diabetics without DPN; no intervention

Other: no intervention

Diabetics with DPN

diabetics with DPN; no intervention

Other: no intervention

Interventions

This study evaluates s system intended to detect bio-markers of DPN. No interventions are involved in this non-invasive study.

Control groupDiabetics with DPNDiabetics without DPN

Eligibility Criteria

Age35 Years - 76 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study population consists of diabetic and non-diabetic individuals who are otherwise healthy.

You may qualify if:

  • Must be non-diabetic or diagnosed as diabetic for at least 5 years

You may not qualify if:

  • history of chemotherapy
  • surgery below the knee within the last 2 years
  • fractures below the know within the last 2 years
  • history of stroke
  • body mass index (BMI) greater than 35
  • history of heart failure
  • peacemaker or implantable cardiovascular defibrillator
  • high blood pressure (over 180/100)
  • end-stage renal (kidney) disease or renal (kidney) transplant
  • peripheral edema greater than 2+ (swelling of the feet or hands)
  • diabetic foot ulcers
  • foot sores
  • Raynaud's phenomenon
  • tobacco use within the last month.
  • treatment with glucocorticoids, including:
  • +10 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VisionQuest Biomedical LLC

Albuquerque, New Mexico, 87106, United States

Location

MeSH Terms

Conditions

Diabetic NeuropathiesDiabetic FootDiabetic Retinopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesDiabetic AngiopathiesVascular DiseasesCardiovascular DiseasesFoot UlcerLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesRetinal DiseasesEye Diseases

Study Officials

  • Peter Soliz, PhD

    VisionQuest Biomedical LLC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 16, 2017

First Posted

March 3, 2017

Study Start

March 8, 2017

Primary Completion

August 1, 2019

Study Completion

September 1, 2019

Last Updated

October 12, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations