NCT03066089

Brief Summary

This study is an open label, two armed trial evaluating the safety and efficacy of Fenfuro capsule twice daily for 90 days in 100 patients with type 2 diabetes that will be conducted in single center in India. The primary outcome measures will be the determination of decrease in plasma glucose levels from baseline to last visit. The secondary outcome will be the determination of safety of Fenfuro capsule in type 2 diabetic subjects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
104

participants targeted

Target at P50-P75 for phase_4 type-2-diabetes-mellitus

Timeline
Completed

Started Dec 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 14, 2015

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

November 1, 2016

Completed
4 months until next milestone

First Posted

Study publicly available on registry

February 28, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2017

Completed
Last Updated

January 31, 2018

Status Verified

June 1, 2017

Enrollment Period

1.8 years

First QC Date

November 1, 2016

Last Update Submit

January 29, 2018

Conditions

Keywords

FBS,HbA1C, PPBS

Outcome Measures

Primary Outcomes (2)

  • Change in Fasting Blood Sugar

    On completion of treatment (i.e.12 weeks) as compared to baseline

  • Change in Postprandial sugar

    On completion of treatment (i.e.12 weeks) as compared to baseline

Secondary Outcomes (2)

  • Change in HbA1c levels

    On completion of treatment (i.e.12 weeks) as compared to baseline

  • SGPT,SGOT,ALP,Creatinine,TLC,DLC & Hb

    On completion of treatment (i.e.12 weeks) as compared to baseline

Study Arms (2)

Group A

EXPERIMENTAL

Fenfuro 500 mg capsule by mouth, BD (two times a day), till next follow-up

Drug: Fenfuro

Group B

NO INTERVENTION

Investigational product is not being administered to this arm. This arm will regularly be observed on follow-up and laboratory investigations will be performed.

Interventions

Also known as: Fenugreek seed extract
Group A

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Agrees to written as well as audio-visual informed consent.
  • Patients of either sex.
  • Aged 18-65 years.
  • Fasting plasma glucose level \<180 mg/dL.
  • HbA1c level more than 7.5%.
  • Not receiving any steroids.
  • Patient on anti-diabetic therapy.

You may not qualify if:

  • Uncooperative Subjects.
  • Diabetes other than type-2 diabetes mellitus.
  • Evidence of renal \& liver disease.
  • History of any hemoglobinopathy that may affect determination of HbA1c.
  • Lactating and Pregnant or planning to conceive females.
  • Physically/ mentally unwell as certified by physician-in-charge.
  • Participation in any other clinical trial with in the last 30 days.
  • Subjects with allergy to investigational product.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gian Sagar Medical College & Hospital

Rajpura, Punjab, 140601, India

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

fenugreek seed meal

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 1, 2016

First Posted

February 28, 2017

Study Start

December 14, 2015

Primary Completion

October 1, 2017

Study Completion

October 1, 2017

Last Updated

January 31, 2018

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations