Taiwan Health Promotion Intervention Study for Elders
THISCE
1 other identifier
interventional
1,080
0 countries
N/A
Brief Summary
Objectives: 1-year multidomain health promotion on prevention of physical and cognitive decline for community-living older people. Design: Methods: Randomized controlled trial Setting: Five cities(Taipei, Taichung, Kaohsiung, Kinmen, I-Lan) in Taiwan Participants: age 65 or older community-dwelling prefrail or frail adults Intervention: 1-year multidomain health promotion (physical, cognitive, nutritional intervention) Measurements: Primary outcome includes frailty status and cognitive performance. Secondary outcomes include depressive symptoms, nutrition assessment, and functional capacity; All the variables were measured at 0, 6, 12 months. The effect of intervention was investigated by intention-to-treat analysis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2014
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 30, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 5, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
July 24, 2016
CompletedFirst Submitted
Initial submission to the registry
February 2, 2017
CompletedFirst Posted
Study publicly available on registry
February 17, 2017
CompletedFebruary 17, 2017
February 1, 2017
1.1 years
February 2, 2017
February 14, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Change from baseline frailty score at 12 months
Measured by Cardiovascular Health Study(CHS) definition
12 months
Study Arms (2)
active control
ACTIVE COMPARATORHealth promotion provided by local health bureau.
multidomain intervention
EXPERIMENTAL1-year multidomain health promotion (physical activities, cognitive training, nutritional sessions)
Interventions
1-year multidomain health promotion (physical, cognitive, nutritional intervention)
Eligibility Criteria
You may qualify if:
- Prefrail or frail community-dwelling people
You may not qualify if:
- Institutionalized or ADL dependent
- Diagnosed dementia
- Limited life expectancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Ho MY, Lee WJ, Yen KH, Liang CK, Peng LN, Lin MH, Loh CH, Hsiao FY, Chen LK. Tailoring multidomain intervention programs to reduce cognitive and physical decline in older adults: Examining rural-urban differences in a nationwide cluster-randomized controlled trial. J Prev Alzheimers Dis. 2025 Sep;12(8):100231. doi: 10.1016/j.tjpad.2025.100231. Epub 2025 Jun 12.
PMID: 40514302DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Liang-Kung Chen, MD, PhD
Director, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
February 2, 2017
First Posted
February 17, 2017
Study Start
August 30, 2014
Primary Completion
October 5, 2015
Study Completion
July 24, 2016
Last Updated
February 17, 2017
Record last verified: 2017-02
Data Sharing
- IPD Sharing
- Will not share