NCT03052803

Brief Summary

The aim of the study is to compare different devices available to measure fractional flow reserve (FFR) in coronary arteries.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2017

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

February 10, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 14, 2017

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

January 25, 2018

Status Verified

December 1, 2017

Enrollment Period

10 months

First QC Date

February 10, 2017

Last Update Submit

January 24, 2018

Conditions

Keywords

coronary stenosisfractional flow reserve

Outcome Measures

Primary Outcomes (3)

  • Simultaneous FFR measure SJM and ACIST

    Correlation between simultaneous measures with St Jude medical FFR device and ACIST device

    Immediately

  • Simultaneous FFR measure Boston Scientific and ACIST

    Correlation between simultaneous measures with BOSTON Scientific FFR device and ACIST device

    Immediately

  • Simultaneous FFR measure Boston Scientific and SJM

    Correlation between simultaneous measures with BOSTON Scientific FFR device and St Jude Medical device

    Immediately

Secondary Outcomes (3)

  • FFR SJM or Boston alone versus simultaneous with ACIST

    Immediately

  • Clinical concordance

    Immediately

  • Drift of the signal

    immediately

Interventions

Comparison of different devices measuring fractional flow reserve

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Consecutifs patients hospitalized for coronary angiography and presenting one or several coronary stenosis needing FFR evaluation

You may qualify if:

  • Patients hospitalized at Caen University Hospital for coronary angiography
  • Coronary stenosis needing FFR evaluation according to recommendations
  • More than 18 years old
  • Clinically stable
  • De novo coronary stenosis
  • Affiliated to social security
  • Informed consent signed

You may not qualify if:

  • Unstable patients defined by acute coronary syndrome \< 7 days
  • Contre-indication to adenosine administration (asthma, allergy, high grade atrio-ventricular bloc without pace maker)
  • History of coronary artery bypass
  • intra-stent restenosis
  • Patient not capable of understanding the study
  • Informed consent not signed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CAEN University Hospital

Caen, France

Location

MeSH Terms

Conditions

Coronary Artery DiseaseCoronary StenosisMyocardial Ischemia

Condition Hierarchy (Ancestors)

Coronary DiseaseHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2017

First Posted

February 14, 2017

Study Start

February 1, 2017

Primary Completion

December 1, 2017

Study Completion

December 1, 2017

Last Updated

January 25, 2018

Record last verified: 2017-12

Data Sharing

IPD Sharing
Will not share

Locations