NCT03051919

Brief Summary

Laparoscopic sleeve gastrectomy is a technically simple popular bariatric operation with acceptable results. Leaks can occur in long staple lines; therefore, variable reinforcement methods are used.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
118

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2014

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2014

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2014

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

April 1, 2015

Completed
1.9 years until next milestone

First Posted

Study publicly available on registry

February 14, 2017

Completed
Last Updated

February 23, 2017

Status Verified

February 1, 2017

Enrollment Period

6 months

First QC Date

April 1, 2015

Last Update Submit

February 18, 2017

Conditions

Keywords

Laparoscopic sleeve gastrectomyreinforcementleak

Outcome Measures

Primary Outcomes (1)

  • assessing prevalence of leaks among different reinforcement methods

    observation

    3 months

Study Arms (4)

no reinforcement

Group I: 25 patients; no reinforcement (NoR) Observation : Patients would be followed up for any signs of leaks. If any, treatment would be offered appropriataly but the results of treatment are not affiliated as a part in the study.

Other: observation

fibrin glue

Group II: 26 patients; fibrin glue (FG) Observation : Patients would be followed up for any signs of leaks. If any, treatment would be offered appropriataly but the results of treatment are not affiliated as a part in the study.

Other: observation

suture reinforcement

Group III: 44 patients; suture reinforcement with 2-0 polypropylene suture (S) Observation : Patients would be followed up for any signs of leaks. If any, treatment would be offered appropriataly but the results of treatment are not affiliated as a part in the study.

Other: observation

biological buttressing materaia

Group IV: 14 patients; biological buttressing material Observation : Patients would be followed up for any signs of leaks. If any, treatment would be offered appropriataly but the results of treatment are not affiliated as a part in the study.

Other: observation

Interventions

biological buttressing materaiafibrin glueno reinforcementsuture reinforcement

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

118 patients with body mass index \>40 kg/m2 underwent sleeve gastrectomy and were enrolled into four groups

You may qualify if:

  • body mass index \>40 kg/m2

You may not qualify if:

  • disruption of the resected stomach during extraction from the abdomen.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Biospecimen

Retention: SAMPLES WITHOUT DNA

resected stomachs

MeSH Terms

Interventions

Observation

Intervention Hierarchy (Ancestors)

MethodsInvestigative Techniques

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Surgeon, Department of Surgery

Study Record Dates

First Submitted

April 1, 2015

First Posted

February 14, 2017

Study Start

March 1, 2014

Primary Completion

September 1, 2014

Study Completion

October 1, 2014

Last Updated

February 23, 2017

Record last verified: 2017-02