NCT03048396

Brief Summary

Transplantation of an uterus

Trial Health

83
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
55mo left

Started Oct 2016

Longer than P75 for not_applicable

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress68%
Oct 2016Dec 2030

Study Start

First participant enrolled

October 1, 2016

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

December 31, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 9, 2017

Completed
13.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2030

Last Updated

January 26, 2026

Status Verified

January 1, 2026

Enrollment Period

14.2 years

First QC Date

December 31, 2016

Last Update Submit

January 23, 2026

Conditions

Resolve Infertility

Outcome Measures

Primary Outcomes (3)

  • Number of patients who are interested in an uterus transplantation

    3 years

  • Number of patients from these who do have a potential donor

    3 years

  • Number of patients from these who do have a medical indication for an uterus transplantation

    3 years

Study Arms (1)

Uterus transplantation

EXPERIMENTAL
Procedure: Uterus transplantation

Interventions

Uterus transplantationPROCEDURE
Uterus transplantation

Eligibility Criteria

Age20 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age below 40 years
  • absolute uterine factor infertility
  • BMI \< 30

You may not qualify if:

  • systemic disease
  • psychiatric disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Brucker SY, Brannstrom M, Taran FA, Nadalin S, Konigsrainer A, Rall K, Scholler D, Henes M, Bosmuller H, Fend F, Nikolaou K, Notohamiprodjo M, Rosenberger P, Grasshoff C, Heim E, Kramer B, Reisenauer C, Hoopmann M, Kagan KO, Dahm-Kahler P, Kvarnstrom N, Wallwiener D. Selecting living donors for uterus transplantation: lessons learned from two transplantations resulting in menstrual functionality and another attempt, aborted after organ retrieval. Arch Gynecol Obstet. 2018 Mar;297(3):675-684. doi: 10.1007/s00404-017-4626-z. Epub 2017 Dec 21.

    PMID: 29270725DERIVED

Study Officials

  • Sara Brucker, MD

    Research Institute for Women's Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 31, 2016

First Posted

February 9, 2017

Study Start

October 1, 2016

Primary Completion (Estimated)

December 1, 2030

Study Completion (Estimated)

December 1, 2030

Last Updated

January 26, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share