Long-term Results After Systematic Periodontal Therapy

NCT03048045 | Unknown

• 1 other identifier: 61/15
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Patients who had had systematic periodontal treatment (antiinfective treatment with subgingival debridement under local anaesthesia and if required periodontal surgery) at the Dept. of Periodontology starting from October 2004 are re-examined 10 years +/- 12 months after accomplishment of active periodontal therapy (re-evaluation 1 or 2, start of supportive periodontal treatment) until 100 patients have been enroled. Radiographs (periapicals or panoramics) from start of treatment should be available.

Conditions

Tooth Loss

Keywords

chronic periodontitis; aggressive periodontitis; supportive periodontal treatment

Outcome Measures

Primary Outcomes (1)

• tooth loss during supportive periodontal treatment

  tooth loss during supportive periodontal treatment

  10 years

Secondary Outcomes (1)

• clinical attachment loss during supportive periodontal treatment

  10 years

Other Outcomes (1)

• Change of PISA during supportive periodontal treatment

  10 years

Study Arms (1)

Supportive Periodontal Treatment (SPT)

* at least 18 years old. * periodontal treatment (antiinfective therapy with subgingival debridement under local anesthesia and if required periodontal surgery) at the Dept. of Periodontology starting after April 2005 durchgeführt. * complete periodontal charting (PPD and PAL-V at 6 sites per tooth, furcation involvement \[Hamp et al. 1975\] at all furcation sites of multi-rooted teeth) prior to treatment (baseline, T0) and after completion of active periodontal treatment (APT) (reevaluation 1 or 2/start of supportive periodontal therapy, T1) * radiographs of all teeth (periapical radiographs or panoramic radiograph) from baseline * written informed consent

Procedure: Supportive Periodontal Treatment (SPT)

Interventions

Supportive Periodontal Treatment (SPT) PROCEDURE

Assessment of Gingival Bleeding Index and Plaque Control Record, re-instruction and re-motivation to effective individual plaque control, professional tooth cleaning, application of a fluoride gel. Twice a year a periodontal charting with probing pocket depths (PPD) and vertical attachment Level (PAL-V) are obtained at 6 sites per tooth. Thirty seconds after probing bleeding on probing (BOP) is recorded. Sites exhibiting PPD = 4 mm and BOP as well as sites with PPD \>/= 5 mm are scaled subgingivally. Assignment of SPT intervals is performed according to the periodontal risk assessment (PRA).

Supportive Periodontal Treatment (SPT)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who had had systematic periodontal treatment (antiinfective treatment with subgingival debridement under local anaesthesia and if required periodontal surgery) at the Dept. of Periodontology starting from October 2004 are re-examined 10 years +/- 12 months after accomplishment of active periodontal therapy (re-evaluation 1 or 2, start of supportive periodontal treatment) until 100 patients have been enroled. Radiographs (periapicals or panoramics) from start of treatment should be available.

You may qualify if:

• at least 18 years old
• systematic periodontal treatment (antiinfective treatment with subgingival debridement under local anaesthesia according to the full mouth disinfection protocol and if required periodontal surgery) at the Dept. of Periodontology starting from October 2004
• complete periodontal charts (probing pocket depths \[PPD\] and vertical probing attachment level \[PAL-V\] at 6 sites per tooth, furcation involvement at all furcation sites of multi-rooted teeth) Prior to periodontal treatment (baseline, T0) and after accomplishment of active periodontal Treatment (APT) (reevaluation 1 or 2 and start of SPT, T1)
• radiographs of all teeth (periapical or panoramic) at baseline
• written informed consent
• younger than 18 years
• no systematic periodontal treatment (antiinfective treatment with subgingival debridement under local anaesthesia according to the full mouth disinfection protocol and if required periodontal surgery) at the Dept. of Periodontology starting from October 2004
• missing complete periodontal charts (probing pocket depths \[PPD\] and vertical probing attachment level \[PAL-V\] at 6 sites per tooth, furcation involvement at all furcation sites of multi-rooted teeth) Prior to periodontal treatment (baseline, T0) and after accomplishment of active periodontal Treatment (APT) (reevaluation 1 or 2 and start of SPT, T1)
• no radiographs of all teeth (periapical or panoramic) at baseline
• missing written informed consent.
• Individual dropout criteria:
• \- retraction of consent

Sponsors & Collaborators

• Goethe University: lead

Study Sites (1)

Dept. of Periodontology, Center of Dentistry and Oral Medicine, Johann Wolfgang Goethe-University

Frankfurt am Main, 60590, Germany

Location

Related Publications (5)

• Petsos H, Ramich T, Nickles K, Dannewitz B, Pfeifer L, Zuhr O, Eickholz P. Tooth loss in periodontally compromised patients: Retrospective long-term results 10 years after active periodontal therapy - tooth-related outcomes. J Periodontol. 2021 Dec;92(12):1761-1775. doi: 10.1002/JPER.21-0056. Epub 2021 May 6.

  PMID: 33748997 RESULT

• Petsos H, Schacher B, Ramich T, Nickles K, Dannewitz B, Arendt S, Seidel K, Eickholz P. Retrospectively analysed tooth loss in periodontally compromised patients: Long-term results 10 years after active periodontal therapy-Patient-related outcomes. J Periodontal Res. 2020 Dec;55(6):946-958. doi: 10.1111/jre.12786. Epub 2020 Jul 22.

  PMID: 33145760 RESULT

• Graetz C, Baumer A, Eickholz P, Kocher T, Petsos H, Pretzl B, Schwendicke F, Holtfreter B. Long-term tooth retention in periodontitis patients in four German university centres. J Dent. 2020 Mar;94:103307. doi: 10.1016/j.jdent.2020.103307. Epub 2020 Feb 26.

  PMID: 32112911 RESULT

• Schroder M, Buchinger M, Dahmer I, Eickholz P, Petsos H. Clinical Treatment Endpoints After Active Periodontal Treatment and 10 Years of Supportive Periodontal Care: A Retrospective Cohort Study. J Clin Periodontol. 2025 Oct;52(10):1386-1397. doi: 10.1111/jcpe.14179. Epub 2025 Jul 8.

  PMID: 40629762 DERIVED

• Vogt L, Pretzl B, Eickholz P, Ramich T, Nickles K, Petsos H. Oral health-related quality of life and patient-reported outcome measures after 10 years of supportive periodontal care. Clin Oral Investig. 2023 Jun;27(6):2851-2864. doi: 10.1007/s00784-023-04876-9. Epub 2023 Feb 1.

  PMID: 36723714 DERIVED

MeSH Terms

Conditions

Tooth Loss; Chronic Periodontitis; Aggressive Periodontitis

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Tooth Diseases; Periodontitis; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Peter Eickholz, Prof. Dr.

  Goethe University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr. Peter Eickholz

Study Record Dates

• First Submitted: February 7, 2017
• First Posted: February 9, 2017
• Study Start: June 1, 2015
• Primary Completion: December 1, 2024
• Study Completion: March 1, 2025
• Last Updated: April 11, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share

Locations

DE (1)