NCT03045822

Brief Summary

There are an increase number of patients with cardiac implantable electronic devices (CIEDs) such as pacemakers (PM) and implantable cardioverter-defibrillators (ICDs) worldwide. The current medical practice guidelines warn on performing bioimpedance analysis (BIA) in this group of patients to avoid any electromagnetic interference. These recommendations restrict the use of BIA in many patients with heart failure in whom BIA might be of great interest in detecting peripheral congestion and in guidance of treatment. However, it is not well known whether BIA can affect the function of cardiac devices. Investigators aimed to test the incidence of electromagnetic interference between BIA and CIEDs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Mar 2014

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 18, 2014

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2016

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 16, 2017

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

January 26, 2017

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 8, 2017

Completed
Last Updated

February 8, 2017

Status Verified

February 1, 2017

Enrollment Period

2 years

First QC Date

January 26, 2017

Last Update Submit

February 3, 2017

Conditions

Keywords

Bioimpedance analysisimplantable cardioverter-defibrillatorspacemakers

Outcome Measures

Primary Outcomes (1)

  • Assessing a change in CIEDs function while and after bioimpedance analysis

    at 6 months

Secondary Outcomes (1)

  • Lead noise loss, over or under sensing of CIEDs

    At 6 months

Study Arms (1)

Patients with cardiac implantable electronic devices

EXPERIMENTAL
Drug: Bioimpedance analysis

Interventions

Patients with cardiac implantable electronic devices

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patient having a cardiac device with or without cardiac resynchronization
  • years of age and above
  • Patients with no pacing-dependent status
  • Patients who read, understood and signed written informed consent letter

You may not qualify if:

  • Patients with acute heart failure
  • Patients implanted in less than 2 months
  • Patients with a particular device lead model prone to develop electronical problems such as Sprint Fidelis of Medtronic (Minneapolis, USA) or Riata of St. Jude Medical (St. Paul, USA)
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

Location

Related Publications (1)

  • Chabin X, Taghli-Lamallem O, Mulliez A, Bordachar P, Jean F, Futier E, Massoullie G, Andonache M, Souteyrand G, Ploux S, Boirie Y, Richard R, Citron B, Lusson JR, Godet T, Pereira B, Motreff P, Clerfond G, Eschalier R. Bioimpedance analysis is safe in patients with implanted cardiac electronic devices. Clin Nutr. 2019 Apr;38(2):806-811. doi: 10.1016/j.clnu.2018.02.029. Epub 2018 Mar 2.

Study Officials

  • Frédéric JEAN

    University Hospital, Clermont-Ferrand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Masking Details
open
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 26, 2017

First Posted

February 8, 2017

Study Start

March 18, 2014

Primary Completion

February 28, 2016

Study Completion

January 16, 2017

Last Updated

February 8, 2017

Record last verified: 2017-02

Locations