NIRS Measurement After SCP Block

NCT03044496 | Completed

• 1 other identifier: NIRS after SCP block
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

Peripheral regional anesthesia induces a sympathectomy-like effect with neurovascular changes causing increased arterial blood flow and venodilatation . Near-infrared spectroscopy (NIRS) can be applied to different kinds of tissue providing oxygen saturation by detecting the absorption and reflection of near-infrared light . The effect on peripheral tissue oxygenation in patients undergoing arteriovenous fistula revision has not yet been examined. We postulate an increase in tissue oxygenation by sympathicolysis caused by peripheral regional anesthesia that might be the reason for beneficial outcome. The aim of our study was to demonstrate the effect of a supraclavicular plexus block in this group of patients.

Conditions

Arterio-venous Fistula

Keywords

NIR Spectroscopy; Nerve Blockade; Surgical Arteriovenous Shunt

Outcome Measures

Primary Outcomes (1)

• NIRS after block

  Absolute change from baseline value in tissue oxygenation

  5 minutes before block until 30 minutes after block

Secondary Outcomes (1)

• Difference between both arms

  5 minutes before block until 30 minutes after block

Study Arms (1)

Supraclavicular Nerve Block

Patients undergoing vascular surgery for creation or revision of an arterio-venous fistula. Intervention: supraclavicular plexus block for anaesthesia. NIRS measurement before and after brachial plexus block.

Drug: Supraclavicular nerve block

Interventions

Supraclavicular nerve block DRUG

Supraclavicular nerve block using ultrasound and 10ml ropivacaine 0.5% with 20ml mepivacaine 1%

Supraclavicular Nerve Block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients undergoing shunt surgery under supraclavicular plexus block

You may qualify if:

• all patients undergoing surgery under regional anaesthesia

You may not qualify if:

• patients refusal

Sponsors & Collaborators

• Marienhospital Stuttgart: lead

Study Sites (1)

Marienhospital Stuttgart, Dpt. of Anaesthesiology

Stuttgart, Baden-Wurttemberg, 70199, Germany

Location

Related Publications (1)

• Keuler J, Weiss C, Klemm K, Pochhammer J, Schmidt R, Ilies C. Assessing changes in tissue oxygenation by near-infrared spectroscopy following brachial plexus block for arteriovenous fistula surgery: A prospective observational pilot study. Eur J Anaesthesiol. 2018 Oct;35(10):759-765. doi: 10.1097/EJA.0000000000000871.

  PMID: 30124502 DERIVED

MeSH Terms

Conditions

Arteriovenous Fistula

Condition Hierarchy (Ancestors)

Arteriovenous Malformations; Vascular Malformations; Cardiovascular Abnormalities; Cardiovascular Diseases; Vascular Fistula; Vascular Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Fistula; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Assistant Medical Director Dpt. for Anaesthesiology

Study Record Dates

• First Submitted: January 31, 2017
• First Posted: February 7, 2017
• Study Start: September 1, 2016
• Primary Completion: September 1, 2017
• Study Completion: January 1, 2018
• Last Updated: April 12, 2018

Record last verified: 2018-04

Data Sharing

• IPD Sharing: Will not share

Locations

DE (1)