NCT03042845

Brief Summary

The investigators aim to assess safety and efficiency of Tiger II (5Fr; Terumo Interventional Systems, Somerset, New Jersey) vs Judkins (5Fr; 3.5L/4R, Medtronic Co) catheters, in coronary angiography via the right transradial route. This is a prospective, randomized, two-centre, study of parallel design. Consecutive patients with acute coronary syndrome (ACS), eligible for non-urgent coronary angiography, are randomized after successful cannulation of right radial artery and informed consent to either Tigger II or Judkins 3.5L/4R catheters.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
640

participants targeted

Target at P75+ for not_applicable coronary-artery-disease

Timeline
Completed

Started Oct 2016

Shorter than P25 for not_applicable coronary-artery-disease

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2016

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 1, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 3, 2017

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 25, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 25, 2017

Completed
Last Updated

May 30, 2017

Status Verified

May 1, 2017

Enrollment Period

8 months

First QC Date

February 1, 2017

Last Update Submit

May 25, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Contrast volume

    Contrast volume (in ml) between groups used for completion of coronary angiogram in intention to treat analysis analysis

    End of coronary angiography

Secondary Outcomes (10)

  • Contrast volume

    End of coronary angiography

  • Dose Area Product (DAP)

    End of coronary angiography

  • Fluoroscopy time

    End of coronary angiography

  • Contrast induced nephropathy (CIN)

    End of coronary angiography

  • Catheter failure

    End of coronary angiography

  • +5 more secondary outcomes

Study Arms (2)

Judkins L3.5/R4 cardiac catheters

ACTIVE COMPARATOR
Device: Judkins 3.5L/4R cardiac catheters

Tiger cardiac catheter

EXPERIMENTAL
Device: Tiger cardiac catheter

Interventions

Tiger cardiac catheter

Tiger cardiac catheter

Judkins 3.5L/4R cardiac catheters

Judkins L3.5/R4 cardiac catheters

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Written informed consent
  • Indication for non-urgent coronary angiography
  • Successful cannulation of right radial artery
  • Availability of both Tiger and JL3.5/JR4 catheters

You may not qualify if:

  • Indication for urgent coronary angiography (ST-elevation myocardial infarction or non ST-elevation myocardial infarction with indication for coronary angiogram within 2 hours)
  • Hemodynamic instability
  • Non palpable right coronary artery
  • Abnormal Allen test
  • Prior coronary artery bypass grafting
  • Chronic kidney disease or dialysis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Patras University Hospital

Pátrai, Achaia, 26500, Greece

Location

Second Department of Cardiology, Red Cross General Hospital

Athens, Greece

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Cardiologist

Study Record Dates

First Submitted

February 1, 2017

First Posted

February 3, 2017

Study Start

October 1, 2016

Primary Completion

May 25, 2017

Study Completion

May 25, 2017

Last Updated

May 30, 2017

Record last verified: 2017-05

Locations