NCT03040843

Brief Summary

Altered mental status (AMS) is common in older patients. However there is a lack of standardization in the definition and documentation of this compliant. Different perception of AMS can cause negative impact on interpretation and obtaining scientific data. Although definition of AMS is so complicated, clinical documentation can be detected in these patients with AMS.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 25, 2016

Completed
7 days until next milestone

Study Start

First participant enrolled

January 1, 2017

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 2, 2017

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

September 21, 2017

Status Verified

September 1, 2017

Enrollment Period

5 months

First QC Date

December 25, 2016

Last Update Submit

September 20, 2017

Conditions

Keywords

documentationaltered mental statusdefinitionclinically

Outcome Measures

Primary Outcomes (2)

  • Detection of impaired level of consciousness in older ED patients

    Arousal (level of consciousness) measured by the Richmond Agitation and Sedation Scale.

    First 30 minute of presentation to the emergency department

  • Detection of impaired content of consciousness in older ED patients

    Awareness (content of consciousness) measured by the 5 criteria list questionnaire.

    First 30 minute of presentation to the emergency department

Secondary Outcomes (1)

  • Mortality

    1 and 3 month mortality after patient enrolled

Eligibility Criteria

Age65 Years - 110 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

All older emergency department patients aged 65 and older.

You may qualify if:

  • All older ED patients

You may not qualify if:

  • Unknown baseline status, any trauma, and unable to assess mental status due to acute clinical condition (STE MI, severe dyspnea, etc)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nevsehir State Hospital

Nevşehir, Turkey (Türkiye)

Location

Related Publications (3)

  • Aslaner MA, Boz M, Celik A, Ahmedali A, Eroglu S, Metin Aksu N, Eroglu SE. Etiologies and delirium rates of elderly ED patients with acutely altered mental status: a multicenter prospective study. Am J Emerg Med. 2017 Jan;35(1):71-76. doi: 10.1016/j.ajem.2016.10.004. Epub 2016 Oct 5.

    PMID: 27765479BACKGROUND
  • Han JH, Wilber ST. Altered mental status in older patients in the emergency department. Clin Geriatr Med. 2013 Feb;29(1):101-36. doi: 10.1016/j.cger.2012.09.005.

    PMID: 23177603BACKGROUND
  • European Delirium Association; American Delirium Society. The DSM-5 criteria, level of arousal and delirium diagnosis: inclusiveness is safer. BMC Med. 2014 Oct 8;12:141. doi: 10.1186/s12916-014-0141-2.

    PMID: 25300023BACKGROUND

MeSH Terms

Conditions

Consciousness Disorders

Condition Hierarchy (Ancestors)

Neurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Emergency Physician

Study Record Dates

First Submitted

December 25, 2016

First Posted

February 2, 2017

Study Start

January 1, 2017

Primary Completion

June 1, 2017

Study Completion

June 1, 2017

Last Updated

September 21, 2017

Record last verified: 2017-09

Locations