Clinical Assessment of Caries and Dental Plaque Based on Auto-fluorescence Imaging System

NCT03038412 | Unknown

• 1 other identifier: DHZhejiangU1
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study was to evaluate the applicability of auto-fluorescence imaging system to detect and quantify caries and dental plaque. Participants were advised to rinse their mouth with distilled water to exclude any chance of fluorescence from food debris. A well trained physicist majored in optical spectroscopy captured auto-fluorescence images of buccal aspects of two maxillary central incisors and occlusal aspects of four first molars from each patient in a dark room. Then they chewed a disclosing agent to assess the Quigley Hein plaque index modified by Turesky of each tooth. Furthermore, participants were also required to brush their teeth for 3min, then International Caries Detection and Assessment System（ICDAS）codes of relevant teeth to evaluate degrees of caries were recorded by an experienced dentist using a mouth mirror and explorer. The Spearman rank correlation coefficient between colorimetric parameters of fluorescence image and the plaque index and ICDAS code were calculated to evaluate the sensitivity and specificity of auto-fluorescence imaging system.

Conditions

Dental Caries (Diagnosis); Dental Plaque; Optical Imaging

Outcome Measures

Primary Outcomes (3)

• Auto-fluorescence image assessment

  Colorimetric parameters of auto-fluorescence images of buccal aspects of two maxillary central incisors and occlusal aspects of four first molars from each patient were calculated to get the Percentage Plaque Index (PPI). PPI is defined as the ratio between area of dental plaque on teeth and the whole teeth area.

  1 week after image collection

• The Quigley Hein plaque index modified by Turesky

  After disclosing dental plaque, plaque index was evaluated as following scoring system:0 no plaque; 1. separate flecks of plaque at the cervical margin of the margin of the tooth; 2. a thin continuous band of plaque (up to 1 mm) at the cervical margin; 3. a band of plaque wider than 1 mm but covering less than (1/3)rd of crown; 4. plaque covering at least (1/3)rd but less than (2/3)rd of the crown; 5. plaque covering (2/3)rd or more of the crown

  right after disclosing

• ICDAS scoring results

  After brushing teeth, ICDAS codes were recorded by an experienced dentist using a mouth mirror and explorer:0 sound； 1. first visual change in enamel; 2. distinct visual change in enamel; 3. localized enamel breakdown; 4. underlying dentine shadow; 5. distinct cavity with visible dentine; 6. extensive cavity within visible dentine.

  right after oral detection

Eligibility Criteria

• Age: 18 Years - 54 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of 60 patients are from the Affiliated Stomatology Hospital of Medical College, Zhejiang University. They have caries in their mouth and need to be treated by dentists with filling cavity. Two maxillary central incisors and four first molars exist in each patient.

You may qualify if:

• Subjects were required to:
• \. have two maxillary central incisors and four first molars in mouth;
• \. have caries in their mouth or have a high risk to get caries and need to be treated by dentists ;
• \. sign informed consent form.

You may not qualify if:

• two incisors and four first molars of participants ever received endodontics treatment;
• \. history of antibiotics, mouthwashes, or any periodontal treatment during the last 3 months;
• with calculus and cementum exposed in tooth cervical;
• \. active systemic disease;
• \. physical or mental disability;
• \. pregnant or lactating.

Sponsors & Collaborators

• Hui Chen: lead

MeSH Terms

Conditions

Dental Caries; Disease; Dental Plaque

Condition Hierarchy (Ancestors)

Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Dental Deposits

Study Officials

• Hui Chen

  Affiliated Hospital of Stomatology, College of Medicine, Zhejiang University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 30, 2017
• First Posted: January 31, 2017
• Study Start: May 1, 2016
• Primary Completion: May 1, 2017
• Study Completion: September 1, 2017
• Last Updated: January 31, 2017

Record last verified: 2017-01