NCT03037814

Brief Summary

The purpose of this study is to evaluate and compare the clinical performance of dental restorative materials in Class II cavities of primary molar teeth

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
11mo left

Started Sep 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress84%
Sep 2021Mar 2027

First Submitted

Initial submission to the registry

January 29, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 31, 2017

Completed
4.7 years until next milestone

Study Start

First participant enrolled

September 28, 2021

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 25, 2026

Expected
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 25, 2027

Last Updated

March 15, 2021

Status Verified

March 1, 2021

Enrollment Period

4.8 years

First QC Date

January 29, 2017

Last Update Submit

March 12, 2021

Conditions

Keywords

restorative materialsprimary teethchildren

Outcome Measures

Primary Outcomes (1)

  • Clinical evaluation of restorative materials in class II cavities on primary molar teeth according to the modified USPHS criteria

    Long-term clinical success of different restorative materials in class II cavities on primary molar teeth

    5 years

Study Arms (4)

Compomer

OTHER

Adhesive agent+Compomer

Device: RMGICDevice: GiomerDevice: Amalgam

RMGIC

OTHER

Primer+RMGIC

Device: CompomerDevice: GiomerDevice: Amalgam

Giomer

OTHER

Adhesive Agent+ Giomer

Device: CompomerDevice: RMGICDevice: Amalgam

Amalgam

OTHER

Amalgam

Device: CompomerDevice: RMGICDevice: Giomer

Interventions

CompomerDEVICE

Aesthetic resin dental materials that are used to replace structure loss, commonly for dental caries of primary tooth. Compomers designed to combine the aesthetics of traditional composite resins with the fluoride release and adhesion of glass-ionomer cements.

AmalgamGiomerRMGIC
RMGICDEVICE

Dental restorative materials that are a combination of the desirable properties of glass-ionomer (fluoride release and chemical adhesion) with high strength and low solubility of resins.

AmalgamCompomerGiomer
GiomerDEVICE

Giomers are dental materials that are hybrid of compomers and glass ionomers, and are used to restore dental caries.

AmalgamCompomerRMGIC
AmalgamDEVICE

Amalgam is a silver-colored dental restorative material that can be used to restore both primary and permanent posterior teeth which have dental caries.

CompomerGiomerRMGIC

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Patients and parent of the patients who accept to participate and sign the informed consent
  • Patients who have at least four first and/or second primary molars with proximal caries that require class II restorations
  • Teeth that have healthy lamina dura and periodontal ligament
  • Teeth that have caries lesions extending no more than the outher half of dentin radiographically

You may not qualify if:

  • Patients and parent of the patients who don't accept to participate and sign the informed consent
  • Teeth that are previously restored
  • Patients who are uncooperative
  • Teeth that doesn't have proximal or occlusal contacts with adjacent healthy teeth
  • Patients who have bruxism, skeletal or dental malocclusion
  • Teeth that have developmental defects or anomalies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Officials

  • Zafer C Cehreli, DDS, PhD

    Hacettepe University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Zafer C Cehreli, DDS, PhD

CONTACT

Beste Ozgur, DDS, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof

Study Record Dates

First Submitted

January 29, 2017

First Posted

January 31, 2017

Study Start

September 28, 2021

Primary Completion (Estimated)

July 25, 2026

Study Completion (Estimated)

March 25, 2027

Last Updated

March 15, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Available IPD Datasets

Clinical Study Report (26161601)Access
Clinical Study Report (19953810)Access
Clinical Study Report (12542617)Access

Locations