NCT03036787

Brief Summary

Infant born preterm have an increased risk of adverse long-term developmental outcomes.The risk associated with preterm birth increase as gestational age decreases, and vulnerability remains in extremely- very preterm (\<32 weeks) and moderate- late preterm (\>32 weeks). There are many studies in the literature showed that the prevalence of developmental delay increases with premature birth. However, there is no study in the literature investigates long term follow up motor and cognitive development in subgroups of preterm infants . Hence the aim of this study is to evaluate the differences in motor and cognitive development in moderate-late (\>32 weeks) and extremely-very preterm infants.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Feb 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 9, 2014

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

January 27, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 30, 2017

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 2, 2017

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 27, 2018

Completed
Last Updated

September 28, 2018

Status Verified

September 1, 2018

Enrollment Period

3 years

First QC Date

January 27, 2017

Last Update Submit

September 27, 2018

Conditions

Keywords

Premature Babymotor developmentcognitive development

Outcome Measures

Primary Outcomes (1)

  • Motor development assessed with the Alberta Infant Motor Scale

    The Alberta Infant Motor Scale is going to use

    Each 3 months from beginning to two years

Secondary Outcomes (1)

  • Cognitive development assessed with the Bayley Scales of Infant and Toddler Development

    Each 3 months from beginning to two years

Study Arms (2)

moderate-early preterm infants

infant who births in 32 weeks to 37 weeks with family based intervention

Behavioral: family based intervention

extremely-very preterm infants

infant who births in 27 weeks to 32 weeks with family based intervention

Behavioral: family based intervention

Interventions

behavioural advises to family for normal motor development

extremely-very preterm infantsmoderate-early preterm infants

Eligibility Criteria

AgeUp to 24 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

preterm infants born with \<37 weeks.

You may qualify if:

  • adjusted age of 24 months or less, born with a gestational age of 36 weeks and 6 days or earlier, not having any systemic disease, and accepting to join the study

You may not qualify if:

  • age greater than 24 months and born with a gestational age of 37 weeks or more
  • having major risk factor

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi University, Faculty of Health and Sciences, Department of Physiotherapy and Rehabilitation

Ankara, 06500, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Study Officials

  • Bulent Elbasan, Phd

    Gazi University

    STUDY CHAIR
0

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

January 27, 2017

First Posted

January 30, 2017

Study Start

February 9, 2014

Primary Completion

February 2, 2017

Study Completion

September 27, 2018

Last Updated

September 28, 2018

Record last verified: 2018-09

Locations