A Randomized Controlled Trial for Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients With Xerostomia
Sponsor study identifier
interventional
73
1 country
1
Study Start
March 1, 2017
Actual (reported)Primary Completion
January 30, 2019
Actual (reported)Study Completion
January 30, 2019
Actual (reported)This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 30, 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 25, 2017
Actual (reported)January 30, 2017
Actual (reported)March 1, 2017
Actual (reported)January 30, 2019
Actual (reported)January 30, 2019
Actual (reported)Changes in subjective dry mouth score compared to baseline
Evaluation of subjective dry mouth score by questionaire
Baseline, 1 and 2 months after intervention
Changes in objective dry mouth score compared to baseline
Baseline, 1 and 2 months after intervention
Changes in salivary pH compared to baseline
Baseline, 1 and 2 months after intervention
Changes in salivary buffering capacity compared to baseline
Baseline, 1 and 2 months after intervention
Changes in Candidal counts of saliva compared to baseline
Baseline, 1 and 2 months after intervention
Changes in energy intake compared to baseline
Baseline, 1 and 2 months after intervention
Daily intake of oral moisturizing jelly 5 times/day for two months
Daily use of non-edible oral lubricating gel 5 times/day for two months
Gel-based artificial saliva is an edible non-nutritious gel intended to relieve dry mouth
A non-edible oral lubricating gel for dry mouth patients
Chonburi Cancer Hospital
Chon Buri, Changwat Chon Buri, 20000, Thailand
Lam-Ubol A, Matangkasombut O, Trachootham D, Tarapan S, Sattabanasuk V, Talungchit S, Paemuang W, Phonyiam T, Chokchaitam O, Mungkung OO. Efficacy of gel-based artificial saliva on Candida colonization and saliva properties in xerostomic post-radiotherapy head and neck cancer patients: a randomized controlled trial. Clin Oral Investig. 2021 Apr;25(4):1815-1827. doi: 10.1007/s00784-020-03484-1. Epub 2020 Aug 10.
Nuchit S, Lam-Ubol A, Paemuang W, Talungchit S, Chokchaitam O, Mungkung OO, Pongcharoen T, Trachootham D. Alleviation of dry mouth by saliva substitutes improved swallowing ability and clinical nutritional status of post-radiotherapy head and neck cancer patients: a randomized controlled trial. Support Care Cancer. 2020 Jun;28(6):2817-2828. doi: 10.1007/s00520-019-05132-1. Epub 2019 Nov 15.
Aroonwan Lam-ubol, DDS, PhD
Srinakarinwirot University
73 participants (actual enrollment reported by the registry).
First Submitted
January 25, 2017
First Posted
January 30, 2017
Study Start
March 1, 2017
Actual (reported)Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Primary Completion
January 30, 2019
Actual (reported)Study Completion
January 30, 2019
Actual (reported)Last Updated
February 8, 2019
Record last verified: 2019-02
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Source: ClinicalTrials.gov.
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