Effect of Different Viscous Foods and Liquids on Swallowing Sounds

NCT03024333 | Completed DMC

• 1 other identifier: 0782-16-EP
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study is aimed to establish and identify the normal pattern of swallowing sounds and analyze swallowing sounds of different textured foods and viscous liquids in healthy subjects to provide clinical evidence to update dysphagia patients' food.

Conditions

Deglutition Disorder

Keywords

Dysphagia; Swallowing Sound; Acoustic Analysis

Outcome Measures

Primary Outcomes (4)

• Duration(s) of swallowing sounds among healthy subjects

  Investigators will record the swallowing sound vibrations at the anterior and posterior neck in health subjects, and analyze the duration(s) of swallowing sounds generated by various viscous foods and liquids through the pharynx.

  2 hours

• Amplitude(W/m2) of swallowing sounds among healthy subjects

  Investigators will record the swallowing sound vibrations at the anterior and posterior neck in health subjects, and analyze the amplitude(W/m2) of swallowing sounds generated by various viscous foods and liquids through the pharynx.

  2 hours

• Mean frequency(Hz) of swallowing sounds among healthy subjects

  Investigators will record the swallowing sound vibrations at the anterior and posterior neck in health subjects, and analyze mean frequency(Hz) of swallowing sounds generated by various viscous foods and liquids through the pharynx.

  2 hours

• Power spectrum(W/Hz) of swallowing sounds among healthy subjects

  Investigators will record the swallowing sound vibrations at the anterior and posterior neck in health subjects, and analyze the power spectrum(W/Hz) of swallowing sounds generated by various viscous foods and liquids through the pharynx.

  2 hours

Secondary Outcomes (3)

• Sound duration(s) of coughing sound and throat clearing among healthy subjects

  2 hours

• Mean frequency(Hz) of coughing sound and throat clearing among healthy subjects

  2 hours

• Power spectrum(W/Hz) of coughing sound and throat clearing among healthy subjects

  2 hours

Study Arms (1)

Healthy subjects

Healthy subjects are: 1. Between 19-60 years old 2. Able to sign the informed consent after the whole study is explained to them 3. Self-reporting no history of swallowing disorders, neurological deficits and/or cancer of the mouth, neck or brain, or head or neck surgery 4. Able to sit upright with or without back support of chair 5. No other diseases affect swallowing function

Eligibility Criteria

• Age: 19 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The participants are between 19-60 years old and able to sign the informed consent. According to self-reporting no history of swallowing disorders, neurological deficits and/or cancer of the mouth, neck or brain, or head or neck surgery, they will be able to sit upright with or without back support of chair. They have no poor dentition and neurological conditions. They don't have other diseases like cervical spondylosis, having pain when swallowing like tonsil inflammation, peritonsillar abscess, retropharyngeal abscess, pharyngeal tumor, epiglottis abscess and other diseases of the throat. They have no esophageal diseases such as esophageal cancers, esophageal foreign body feelings, esophagitis or neuromuscular disorders such as esophageal spasm.

You may qualify if:

• Between 19-60 years old
• Able to sign the informed consent after the whole study is explained to them
• Self-reporting no history of swallowing disorders, neurological deficits and/or cancer of the mouth, neck or brain, or head or neck surgery
• Able to sit upright with or without back support of chair
• No other diseases affect swallowing function

You may not qualify if:

• Have poor dentition and neurological conditions.
• Have other diseases like cervical spondylosis, having pain when swallowing like tonsil inflammation, peritonsillar abscess, retropharyngeal abscess, pharyngeal tumor, epiglottis abscess and other diseases of the throat.
• Have esophageal diseases such as esophageal cancers, esophageal foreign body feelings, esophagitis, etc. Neuromuscular disorders such as esophageal spasm.

Sponsors & Collaborators

• University of Nebraska: lead

Study Sites (1)

University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States

Location

MeSH Terms

Conditions

Deglutition Disorders

Condition Hierarchy (Ancestors)

Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Pharyngeal Diseases; Otorhinolaryngologic Diseases

Study Officials

• Chun K Siu, PhD

  University of Nebraska

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 7, 2017
• First Posted: January 18, 2017
• Study Start: May 8, 2017
• Primary Completion: October 12, 2017
• Study Completion: September 17, 2018
• Last Updated: September 15, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)