Trial of Low-cost Microbiological Water Test Kits

NCT03021434 | Completed

• 1 other identifier: 11920/RR/5743
• Study Type: interventional
• Target: 572
• Locations: 0 countries
• Sites: N/A

Brief Summary

The present study is a cluster randomized control trial of low-cost microbiological water test kits in rural and peri-urban communities in the Kanpur region of Uttar Pradesh, India.

Conditions

Diarrhea; E.Coli Infections

Keywords

Water Supply/standards; Water microbiology; India; Hand disinfection; Escherichia coli Infections/prevention & control; Hygiene; Health behavior; Drinking water; Informational intervention

Outcome Measures

Primary Outcomes (1)

• Arithmetic mean E. coli count from sample of stored household drinking water

  A sample of household drinking water will be collected and analyzed in a standard laboratory using membrane filtration.

  1-2 month follow up visit post initial household information session

Secondary Outcomes (2)

• Water storage, handling, and use behaviors

  1-2 month follow up visit post initial household information session

• Intervention uptake/use

  1-2 month follow up visit post initial household information session

Study Arms (3)

Standard Testing

EXPERIMENTAL

Households will participate in community and household water safety education sessions, during which they will be given generalized information on water quality and safe water handling. A water sample from these households will be collected for laboratory analysis. Household-specific water quality information will be delivered to households within 72 hours, and households will be informed whether their drinking water was found to be contaminated. A study team member will review the information from the laboratory tests with the household and review information covered in the informational materials on safe water handling, storage, and use behaviours.

Other: Community and household water safety education sessions; Other: Household-specific water quality information

Test Kits

EXPERIMENTAL

Households will participate in community and household water safety education sessions, during which they will be given generalized information on water quality and safe water handling. Data collectors will demonstrate the use of the low-cost microbiological water test kits and test household stored drinking water. A study team member will return to the household within 72 hours and review the household-specific water quality information from the initial test with household members. Households will be given 10 water test kits to use at their discretion over the 1-2 month follow up period. They will be appropriately trained in how to both perform the test and interpret the results. Households will also review information on safe water handling, storage, and use behaviours.

Other: Community and household water safety education sessions; Other: Household-specific water quality information; Other: Low-cost microbiological water test kits

Comparison

ACTIVE COMPARATOR

Households will participate in community and household water safety education sessions, during which they will be given generalized information on water quality and safe water handling. A water sample from these households will be collected for laboratory analysis. Results from this analysis will be returned to the household at project endline. A study team member will return to the household within 72 hours to review the information on safe water handling, storage, and use behaviours.

Other: Community and household water safety education sessions

Interventions

Community and household water safety education sessions OTHER

Data collectors will give a short community presentation on water treatment, as well as safe water handling and storage. Then, data collectors will immediately visit households and review this information. Data collectors will return within 72 hours and review this information once more.

Comparison; Standard Testing; Test Kits

Household-specific water quality information OTHER

Household specific water quality data will be provided in two ways. In the Standard Testing Arm, water quality data will be analyzed in a laboratory by standard methods and results will be delivered to households. In the Test Kit arm, water quality data will be analyzed in households using provided water test kits.

Standard Testing; Test Kits

Low-cost microbiological water test kits OTHER

Intervention component consists of low-cost, biodegradable that tests for the presence of E. coli in water samples. The test uses Aquatest broth medium with resorufin methyl ester chromogen. Presence of E. coli (positive test) imparts bright red color, making it easy to use/interpret at the household level with minimal training

Test Kits

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Village located within the Kanpur district, within
• Village population between 100 and 1000 households.
• No chlorinated water sources available in the village.
• Consent to participate in the study
• Contain at least one child who is between 29 days and 60 months of age at the time of enrollment

You may not qualify if:

• Villages that receive chlorinated water from utility services

Sponsors & Collaborators

• London School of Hygiene and Tropical Medicine: lead
• Indian Institute of Technology Kanpur: collaborator

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MeSH Terms

Conditions

Diarrhea; Escherichia coli Infections; Health Behavior

Interventions

Residence Characteristics

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Enterobacteriaceae Infections; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Behavior

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Robert Dreibelbis, PhD

  London School of Hygiene and Tropical Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 12, 2017
• First Posted: January 16, 2017
• Study Start: January 1, 2017
• Primary Completion: May 25, 2017
• Study Completion: May 25, 2017
• Last Updated: June 29, 2017

Record last verified: 2017-01

Data Sharing

• IPD Sharing: Will not share