NCT03021265

Brief Summary

Study to evaluate real-world safety, effectiveness and appropriate use of Micatrio® Combination Tablets treatment in patients with hypertension

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
676

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 12, 2017

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 13, 2017

Completed
7 days until next milestone

Study Start

First participant enrolled

January 20, 2017

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 11, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 11, 2019

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

May 12, 2020

Completed
Last Updated

May 12, 2020

Status Verified

May 1, 2020

Enrollment Period

2.2 years

First QC Date

January 12, 2017

Results QC Date

April 3, 2020

Last Update Submit

May 7, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Frequency of Patients With Any Suspected Adverse Drug Reactions

    An Adverse drug reaction (ADR) is defined as an AE for which either the investigator or the sponsor (or both) assess the causal relationship to Micatrio Combination Tablets as related. The frequency of patients with any suspected ADR is presented as total number of participants with an ADR reported.

    from first intake of Micatrio combination tablet until last intake +1 day (week 52)

Secondary Outcomes (2)

  • Change From Baseline in Clinic Diastolic Blood Pressure at Week 52

    At baseline and week 52

  • Change From Baseline in Clinic Systolic Blood Pressure at Week 52

    At baseline and week 52

Study Arms (1)

T80/A5/H12.5 FDC

Patients with hypertension

Drug: T80/A5/H12.5 FDC

Interventions

Drug

Also known as: MICATRIO
T80/A5/H12.5 FDC

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

500

You may qualify if:

  • Patients who are prescribed with Micatrio® Combination Tablets by the discretion of investigators based on the Japanese package insert
  • Patients who have never been treated with Micatrio® Combination Tablets before enrolment

You may not qualify if:

  • Patients who are participating/planned to participate in a clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nippon Boehringer Ingelheim Co., Ltd

Tokyo, 4570047, Japan

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Limitations and Caveats

The study was conducted in an unblinded manner and without controls. The explanatory power of the study results was limited and the study results should be interpreted with the necessary caution.

Results Point of Contact

Title
Boehringer Ingelheim, Call Center
Organization
Boehringer Ingelheim

Study Officials

  • Boehringer Ingelheim

    Boehringer Ingelheim

    STUDY CHAIR
  • Rie Ikeda, +81364172200

    zzCDMJP_PV_PMS@boehringer-ingelheim.com

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2017

First Posted

January 13, 2017

Study Start

January 20, 2017

Primary Completion

April 11, 2019

Study Completion

April 11, 2019

Last Updated

May 12, 2020

Results First Posted

May 12, 2020

Record last verified: 2020-05

Locations