NCT03020355

Brief Summary

Comparison of effectiveness of placental blood drainage after spontaneous vaginal delivery in decreasing the duration, blood loss,and complications of the third stage, against no drainage of placental blood.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2017

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 22, 2016

Completed
22 days until next milestone

First Posted

Study publicly available on registry

January 13, 2017

Completed
19 days until next milestone

Study Start

First participant enrolled

February 1, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

January 13, 2017

Status Verified

January 1, 2017

Enrollment Period

3 months

First QC Date

December 22, 2016

Last Update Submit

January 11, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Blood lost

    through delivery completion, an average of 30 minutes

Secondary Outcomes (1)

  • The duration of the third stage

    through the duration of the third stage, an average 45 minutes

Study Arms (2)

Placental Blood Drainage

EXPERIMENTAL

Immediately after vaginal delivery, after clamping and cutting the cord-the cord will unclamped and the blood will drained until the flow ceased.

Procedure: Placental Blood Drainage

not Placental Blood Drainage

ACTIVE COMPARATOR

In the control group, the clamped cord will not released.

Procedure: not Placental Blood Drainage

Interventions

Immediately after vaginal delivery, after clamping and cutting the cord-the cord will unclamped and the blood will drained until the flow ceased.

Placental Blood Drainage

In the control group, the clamped cord will not released.

not Placental Blood Drainage

Eligibility Criteria

Age15 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Singleton pregnancy
  • Vertex presentation
  • Gestational age of 37 weeks (or) more
  • No major medical (or) obstetric complications
  • Spontaneous vaginal delivery

You may not qualify if:

  • Hb\\7 gm/dl
  • History of APH
  • Instrumental delivery
  • Multiple pregnancy
  • Malpresentations
  • Large baby (more than 3.5 kg)
  • Polyhydramnios
  • Known coagulations disorders
  • Previous surgeries on the uterus

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Roy P, Sujatha MS, Bhandiwad A, Biswas B, Chatterjee A. Placental Blood Drainage as a Part of Active Management of Third Stage of Labour After Spontaneous Vaginal Delivery. J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):242-5. doi: 10.1007/s13224-016-0857-3. Epub 2016 Mar 12.

  • Soltani H, Poulose TA, Hutchon DR. Placental cord drainage after vaginal delivery as part of the management of the third stage of labour. Cochrane Database Syst Rev. 2011 Sep 7;2011(9):CD004665. doi: 10.1002/14651858.CD004665.pub3.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor

Study Record Dates

First Submitted

December 22, 2016

First Posted

January 13, 2017

Study Start

February 1, 2017

Primary Completion

May 1, 2017

Study Completion

June 1, 2017

Last Updated

January 13, 2017

Record last verified: 2017-01

Data Sharing

IPD Sharing
Will share