Relationship of Metabolic Syndrome and Its Components With Thyroid Cancer

NCT03006289 | Unknown DMC

• 1 other identifier: qfsnfm-003
• Study Type: observational
• Target: 3,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to investigate the association between metabolic syndrome (MS), body mass index (BMI), hyperglycemia, dyslipidemia, hypertension and thyroid cancer. Screen for the risk factors that affect the incidence of thyroid cancer.

Conditions

Thyroid Cancer

Keywords

Metabolic Syndrome; fasting plasma glucose

Outcome Measures

Primary Outcomes (1)

• lipids

  before the thyroid surgery

Secondary Outcomes (1)

• glucose

  before the thyroid surgery

Other Outcomes (4)

• blood pressure

  before the thyroid surgery

• Uric Acid

  before the thyroid surgery

• sialic acid

  before the thyroid surgery

Study Arms (2)

The thyroid cancer group

The postoperative pathology of thyroid is malignant

The thyroid nodule group

The postoperative pathology of thyroid is benign

Eligibility Criteria

• Age: 8 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients undergone thyroid surgery

You may qualify if:

• patients undergone thyroid surgery
• signed the informed consent

You may not qualify if:

• patients with no surgery

Sponsors & Collaborators

• Lin Liao: lead

Related Publications (3)

• Yao J, Zhao J, Liu J, Jiang S, Guo S, Xu L, Zhang X, Sheng Q, Wang K, Liao L, Dong J. The relationships between thyroid functions of short-term rapid hypothyroidism and blood lipid levels in post-thyroidectomy patients of differentiated thyroid cancer. Front Endocrinol (Lausanne). 2023 Apr 27;14:1114344. doi: 10.3389/fendo.2023.1114344. eCollection 2023.

  PMID: 37181036 DERIVED

• Zhao J, Tian Y, Jia Z, Yao J, Liao L, Dong J. Abnormal Glucose Metabolism Parameters and the Aggressiveness of Differentiated Thyroid Carcinoma: A Hospital-Based Cross-Section Study in China. Front Endocrinol (Lausanne). 2022 Mar 1;13:806349. doi: 10.3389/fendo.2022.806349. eCollection 2022.

  PMID: 35299970 DERIVED

• Zhao J, Tian Y, Yao J, Gu H, Zhang R, Wang H, Liao L, Dong J. Hypercholesterolemia Is an Associated Factor for Risk of Differentiated Thyroid Cancer in Chinese Population. Front Oncol. 2021 Jan 28;10:508126. doi: 10.3389/fonc.2020.508126. eCollection 2020.

  PMID: 33585179 DERIVED

MeSH Terms

Conditions

Thyroid Neoplasms; Metabolic Syndrome

Condition Hierarchy (Ancestors)

Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Endocrine System Diseases; Thyroid Diseases; Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Lin Liao, MD

  Qianfoshan Hospital

  STUDY CHAIR

Central Study Contacts

Lin Liao, MD

CONTACT

8615168888260; liaolin@medmail.com.cn

Study Design

• Study Type: observational
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: chief of endocrinology department at Qianfoshan Hospital

Study Record Dates

• First Submitted: December 26, 2016
• First Posted: December 30, 2016
• Study Start: December 1, 2016
• Primary Completion: October 1, 2017
• Study Completion: November 1, 2017
• Last Updated: December 30, 2016

Record last verified: 2016-12

Data Sharing

• IPD Sharing: Will share