NCT03001856

Brief Summary

This study was conducted to demonstrate the equivalence of wound outcomes between the interrupted oblique intradermal suture (OIS) and conventional interrupted intradermal suture (IS) methods

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
144

participants targeted

Target at P50-P75 for not_applicable surgery

Timeline
Completed

Started Jan 2016

Shorter than P25 for not_applicable surgery

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

December 19, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 23, 2016

Completed
Last Updated

January 10, 2017

Status Verified

January 1, 2017

Enrollment Period

11 months

First QC Date

December 19, 2016

Last Update Submit

January 8, 2017

Conditions

Outcome Measures

Primary Outcomes (4)

  • Modified Hollander Cosmesis Scale (MHCS) at 1st week

    Wound evaluation at 1st week

    1 week

  • Patient and Observer Scar Assessment Scale (POSAS) at 1st week

    Wound evaluation at 1st week

    1 week

  • Modified Hollander Cosmesis Scale (MHCS) at 2nd month

    Wound evaluation at 2nd month

    2nd month

  • Patient and Observer Scar Assessment Scale (POSAS) at 2nd month

    Wound evaluation at 2nd month

    2nd month

Secondary Outcomes (5)

  • Rate of wound dehiscence

    1 week

  • Rate of wound infection

    1 week

  • Suture time

    day 1

  • Number of stitches

    day 1

  • Suture material length

    day 1

Study Arms (2)

Oblique Intradermal Suture

EXPERIMENTAL

OIS is very similar to conventional interrupted intradermal suture (IS), except that the suture in OIS is canted or angled relative to the vertical plane (Figure 1). To perform OIS, the needle is passed from deep to superficial dermis and canted 30°-60° from the normal vertical plane. The needle is then inserted into the opposite wound edge from superficial to deep dermis in a mirror-image fashion. The thread is tied with a square knot to finish the suture.

Procedure: Oblique Intradermal Suture

Intradermal Suture

EXPERIMENTAL

Conventional interrupted intradermal suture

Procedure: Intradermal Suture

Interventions

Oblique Intradermal Suture
Intradermal Suture

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • needs elective surgery with linear incision wound
  • wound length must be 3-12 cm.

You may not qualify if:

  • irregular wound shape
  • asymmetrical wound depth
  • different skin color in wound area
  • contaminated wound
  • mental impairment
  • pregnancy
  • patients with soft tissue disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Wongkietkachorn A, Wongkietkachorn N, Rhunsiri P. Oblique intradermal suture as a faster choice for intradermal closure: a randomized equivalence trial. J Plast Surg Hand Surg. 2019 Feb;53(1):45-50. doi: 10.1080/2000656X.2018.1533476. Epub 2018 Oct 31.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

December 19, 2016

First Posted

December 23, 2016

Study Start

January 1, 2016

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

January 10, 2017

Record last verified: 2017-01