NCT03000010

Brief Summary

The purpose of this study is to evaluate the effectiveness of incisional vacuum-assisted closure (VAC) therapy in the prevention of infection after posterior spinal fusion for pediatric neuromuscular scoliosis, in comparison to a regular gauze bandage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
41

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 16, 2012

Completed
4.4 years until next milestone

First Submitted

Initial submission to the registry

December 18, 2016

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 21, 2016

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 17, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 17, 2020

Completed
12 months until next milestone

Results Posted

Study results publicly available

June 28, 2021

Completed
Last Updated

June 28, 2021

Status Verified

June 1, 2021

Enrollment Period

8 years

First QC Date

December 18, 2016

Results QC Date

June 5, 2021

Last Update Submit

June 5, 2021

Conditions

Keywords

Wound VacNeuromuscular ScoliosisPosterior Spinal Fusion

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Wound Dehiscence or Infection

    Participants with wound dehiscence or infection requiring unplanned dressing changes, antibiotics, or surgery

    2 years

Study Arms (2)

Incisional Wound Vac

ACTIVE COMPARATOR

We will attach sponges and a suction tube to the incision after surgery. We will leave it on for 72 hours. From then on, patients will get the care that patients normally get after spinal fusion surgery.

Device: Incisional Wound Vac

Normal Gauze Bandage Group

ACTIVE COMPARATOR

We will cover patients incision with regular gauze bandages. These are the bandages that patients normally get after spinal fusion surgery. They will be left on for 72 hours.

Other: Standard Bandage

Interventions

Also known as: Incisional vacuum-assisted closure therapy
Incisional Wound Vac
Also known as: Gauze Bandage, Gauze
Normal Gauze Bandage Group

Eligibility Criteria

Age0 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • any patient 17 years and younger
  • neuromuscular scoliosis undergoing posterior spinal fusion

You may not qualify if:

  • idiopathic and congenital scoliosis
  • any type of spine surgery other than posterior spinal fusion (eg. vertical expandable prosthetic titanium rib placement, growing rod placement, anterior spinal fusion)
  • intraoperative dural tear
  • documented allergy to adhesive dressings

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

Results Point of Contact

Title
G. Ying Li
Organization
University of Michigan

Study Officials

  • Ying G Li, MD

    University of Michigan

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

December 18, 2016

First Posted

December 21, 2016

Study Start

July 16, 2012

Primary Completion

July 17, 2020

Study Completion

July 17, 2020

Last Updated

June 28, 2021

Results First Posted

June 28, 2021

Record last verified: 2021-06

Data Sharing

IPD Sharing
Will not share

Locations