The Characteristics of Regional Bone Quality in the Cervical Vertebrae Considering BMD

NCT02995798 | Completed

• 1 other identifier: Anatomy C-Spine
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months) from April 2009 to December 2014. There were 52 females and 47 males. The mean age was 63.7 year (female: 63.4 years, male: 64.1; range 32-86 years). The patient was excluded who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass. Patients were divided into three groups according to femoral neck BMD (Group A, T-score ≥-1; Group B, -2.5\<T-score\<-1.0; Group C, T-score≤-2.5). Group A had normal BMD patients, Group B had lower normal patients including osteopenic patients and Group C presented osteoporotic patients. The mean HU numbers of cortical bone area in the vertebral canal (cHU, the medial wall of the lateral mass), the posterior wall of transverse foramen (fHU), the medial (mHU), lateral wall (lHU) and trabecular area of pedicle (pHU) were measured on the axial CT images in clinical images.

Conditions

Cortical Bone Thickness

Outcome Measures

Primary Outcomes (2)

• Cortical bone Thickness

  two weeks

• HU number

  two weeks

Study Arms (3)

Group A

T-score ≥-1

Other: Cortical Bone thickness and Hounsfield unit (HU) numbers

Group B

-2.5\<T-score\<-1.0

Other: Cortical Bone thickness and Hounsfield unit (HU) numbers

Group C

T-score≤-2.5

Other: Cortical Bone thickness and Hounsfield unit (HU) numbers

Interventions

Cortical Bone thickness and Hounsfield unit (HU) numbers OTHER

Cortical Bone thickness and Hounsfield unit (HU) numbers considering BMD

Group A; Group B; Group C

Eligibility Criteria

• Age: 25 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

You may qualify if:

• Patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

You may not qualify if:

• Who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass.

Sponsors & Collaborators

• Gangneung Asan Hospital: lead
• The Catholic University of Korea: collaborator

Study Sites (1)

Moon-Kyu Kim

Gangneung, Kangwondo, 25440, South Korea

Location

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: December 9, 2016
• First Posted: December 16, 2016
• Study Start: April 1, 2009
• Primary Completion: December 1, 2014
• Study Completion: August 1, 2016
• Last Updated: December 16, 2016

Record last verified: 2016-12

Locations

KR (1)